Interactor 1: CDC20 (P26309)
APC/C activator protein CDC20 (Cell division control protein 20)
Gene: CDC20

Interactor 2: MAD2 (P40958)
Mitotic spindle checkpoint component MAD2 (Mitotic MAD2 protein)
Gene: MAD2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.763

The method score is based on:

Property Details
Experiments 10688190, 9461437, 10848588, 12887895, 15198982, 15879521, 16818718, 28189585, 17634282, 31928870, 23000150, 19143472, 39079532, 10704439, 11726501
Identification Methods two hybrid, coimmunoprecipitation, affinity chromatography technology, pull down, biochemical, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0007094 - mitotic spindle assembly checkpoint signaling
GO:0033597 - mitotic checkpoint complex
GO:0051301 - cell division
GO:1990333 - mitotic checkpoint complex, CDC20-MAD2 subcomplex
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 610
Sc

1 196
+ Ce
+ Dm
+ At
+ Hs
+ Hs
+ At
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025