HitPredict

Interactor 1: UBE2S (Q16763)
Ubiquitin-conjugating enzyme E2 S (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme S) (E2-EPF) (Ubiquitin carrier protein S) (Ubiquitin-conjugating enzyme E2-24 kDa) (Ubiquitin-conjugating enzyme E2-EPF5) (Ubiquitin-protein ligase S)
Gene: UBE2S

Interactor 2: APC11 (Q9NYG5)
Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein)
Gene: ANAPC11

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.993

The method score is based on:

Property Details
Experiments 25306923, 25306918, 32905768, 20080579, 23288039, 23972993, 25490258, 25825779, 26811472, 27120157, 21700221, 27114510, 27522463, 27259151, 27601667, 29517484, 32152539, 32076268, 32307883, 32393902 and 11 others

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Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~zf-ANAPC11
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
and 3 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 222
Hs

1 84
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024