Interactor 1: CDC20 (Q12834)
Cell division cycle protein 20 homolog (p55CDC)
Gene: CDC20

Interactor 2: MD2L1 (Q13257)
Mitotic spindle assembly checkpoint protein MAD2A (HsMAD2) (Mitotic arrest deficient 2-like protein 1) (MAD2-like protein 1)
Gene: MAD2L1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.99 0.60 0.773

The method score is based on:

Property Details
Experiments 20054826, 26496610, 24151075, 26986935, 18318601, 11707408, 21041666, 9736712, 15182668, 9637688, 33961781, 11274370, 33384373, 18592005, 11804586, 20512932, 14561775, 11702782, 21525009, 16497171 and 55 others

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Identification Methods affinity chromatography technology, unspecified method, pull down, two hybrid, x-ray crystallography, anti tag coimmunoprecipitation, molecular sieving, solid phase assay, isothermal titration calorimetry, anti bait coimmunoprecipitation and 2 others

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Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000776 - kinetochore
GO:0000922 - spindle pole
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0007094 - mitotic spindle assembly checkpoint signaling
and 3 others

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Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 499
Hs

1 205
+ Hs
+ Dm
+ Ce
+ Hs
+ At
+ At
+ Sc
+ Hs
+ Hs

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Last updated: 11Aug2025