HitPredict

Interactor 1: DNMT1 (P26358)
DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (CXXC-type zinc finger protein 9) (DNA methyltransferase HsaI) (DNA MTase HsaI) (M.HsaI) (MCMT)
Gene: DNMT1

Interactor 2: PAX6 (P26367)
Paired box protein Pax-6 (Aniridia type II protein) (Oculorhombin)
Gene: PAX6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34459131
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0010628 - positive regulation of gene expression
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1616 Hs			1 422
+	Hs
		685251 PB1_HUMAN (12-1162): 3.52e-179: 584: 15.23		PAX6_HUMAN (1-422): 2.15e-115: 345: 100.00
+	Hs
		1056622 PB1_HUMAN (12-1162): 3.52e-179: 584: 15.23		PAX8_HUMAN (1-418): 7.81e-64: 213: 32.08
+	Hs
		938469 PB1_HUMAN (12-1162): 3.52e-179: 584: 15.23		PAX9_HUMAN (1-196): 1.62e-45: 162: 47.96
+	Hs
		685230 NIPBL_HUMAN (4-361): 1.81e-13: 78.5: 14.14		PAX6_HUMAN (1-422): 2.15e-115: 345: 100.00
+	Hs
		1056615 NIPBL_HUMAN (4-361): 1.81e-13: 78.5: 14.14		PAX8_HUMAN (1-418): 7.81e-64: 213: 32.08
+	Hs
		938459 NIPBL_HUMAN (4-361): 1.81e-13: 78.5: 14.14		PAX9_HUMAN (1-196): 1.62e-45: 162: 47.96