HitPredict

Interactor 1: DNMT1 (P26358)
DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (CXXC-type zinc finger protein 9) (DNA methyltransferase HsaI) (DNA MTase HsaI) (M.HsaI) (MCMT)
Gene: DNMT1

Interactor 2: H4 (P62805)
Histone H4
Gene: H4C1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	30804502, 30021884
Identification Methods	affinity chromatography technology, proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BAH~CENP-T_C
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1616 Hs			1 103
+	Xl
		979440 P79922_XENLA (126-1616): 0: 1498: 70.07		H4_XENLA (1-103): 1.39e-48: 151: 100.00
+	Hs
		979908 PB1_HUMAN (12-1162): 3.52e-179: 584: 15.23		H4_HUMAN (1-103): 1.39e-48: 151: 100.00
+	Nc
		419937 Q3Y3Z1_NEUCR (1040-1604): 3e-121: 418: 22.53		H4_NEUCR (18-103): 6.16e-41: 132: 91.86
+	Hs
		979515 ANK2_HUMAN (15-932): 2.95e-29: 130: 9.73		H4_HUMAN (1-103): 1.39e-48: 151: 100.00
+	Hs
		979834 NIPBL_HUMAN (4-361): 1.81e-13: 78.5: 14.14		H4_HUMAN (1-103): 1.39e-48: 151: 100.00
+	Hs
		980189 MINT_HUMAN (9-691): 1.07e-09: 66: 7.99		H4_HUMAN (1-103): 1.39e-48: 151: 100.00
+	Hs
		980061 TITIN_HUMAN (1-617): 2.23e-09: 64.8: 9.03		H4_HUMAN (1-103): 1.39e-48: 151: 100.00