Interactor 1: ARRB2 (P32121)
Beta-arrestin-2 (Arrestin beta-2) (Non-visual arrestin-3)
Gene: ARRB2

Interactor 2: CLH1 (Q00610)
Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17)
Gene: CLTC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.885

The method score is based on:

Property Details
Experiments 32962859, 9169477, 35044719, unassigned3413
Identification Methods affinity chromatography technology, pull down, phage display, fluorescence polarization spectroscopy
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Arrestin_C~Clathrin_propel
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0031623 - receptor internalization
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 409
Hs

1 1675
+ Hs
+ Bt

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024