Interactor 1: OTX2 (P32243)
Homeobox protein OTX2 (Orthodenticle homolog 2)
Gene: OTX2

Interactor 2: NANOG (Q9H9S0)
Homeobox protein NANOG (Homeobox transcription factor Nanog) (hNanog)
Gene: NANOG

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 26687479
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Homeodomain~Homeodomain
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
and 2 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 289
Hs

1 305
+ Mm
+ Mm
+ Mm
+ Mm
+ Dm
+ Hs
+ Mm
+ Ce
+ Bt
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024