Protein: EFNA1
Ephrin-A1 (EPH-related receptor tyrosine kinase ligand 1) (LERK-1) (Immediate early response protein B61) (Tumor necrosis factor alpha-induced protein 4) (TNF alpha-induced protein 4) [Cleaved into: Ephrin-A1, secreted form]

Gene: EFNA1
Organism: Homo sapiens
Interactions: 93
UniProt ID: P20827

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001525 - angiogenesis
GO:0001934 - positive regulation of protein phosphorylation
GO:0003180 - aortic valve morphogenesis
GO:0003183 - mitral valve morphogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

595974

EPHA2
Ephrin type-A receptor 2

7

20

Small-scale

0.961

High

595985

EPHA4
Ephrin type-A receptor 4

2

20

Small-scale

0.768

High

595975

EPHA3
Ephrin type-A receptor 3

1

20

Small-scale

0.647

High

595968

EFNA1
Ephrin-A1

1

5

High-throughput

0.618

High

595976

EPHB2
Ephrin type-B receptor 2

1

20

High-throughput

0.618

High

595983

EFNA3
Ephrin-A3

1

5

High-throughput

0.618

High

595984

EPHB4
Ephrin type-B receptor 4

1

20

High-throughput

0.618

High

364039

CXCL7
Platelet basic protein

2

0

High-throughput

0.594

High

596014

KAT5
Histone acetyltransferase KAT5

1

0

High-throughput

0.518

High

596021

GARE1
GRB2-associated and regulator of MAPK protein 1

1

0

High-throughput

0.493

High

523516

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.486

High

363718

ALBU
Albumin

1

2

High-throughput

0.479

High

380559

K2C1
Keratin, type II cytoskeletal 1

1

19

High-throughput

0.479

High

393034

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

2

High-throughput

0.479

High

410604

CD5
T-cell surface glycoprotein CD5

1

5

High-throughput

0.479

High

427042

CATD
Cathepsin D

1

1

High-throughput

0.479

High

428018

TBB5
Tubulin beta chain

1

14

High-throughput

0.479

High

443327

VIME
Vimentin

1

20

High-throughput

0.479

High

501672

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.479

High

503421

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

537799

KPYM
Pyruvate kinase PKM

1

1

High-throughput

0.479

High

538099

ENPL
Endoplasmin

1

2

High-throughput

0.479

High

549086

GNS
N-acetylglucosamine-6-sulfatase

1

2

High-throughput

0.479

High

551606

DESP
Desmoplakin

1

5

High-throughput

0.479

High

595969

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

595970

ITA3
Integrin alpha-3

1

3

High-throughput

0.479

High

595973

LYOX
Protein-lysine 6-oxidase

1

4

High-throughput

0.479

High

595982

TMEDA
Transmembrane emp24 domain-containing protein 10

1

1

High-throughput

0.479

High

595987

ACTB
Actin, cytoplasmic 1

1

4

High-throughput

0.479

High

595993

RL23
Large ribosomal subunit protein uL14

1

2

High-throughput

0.479

High

595995

RL11
Large ribosomal subunit protein uL5

1

2

High-throughput

0.479

High

595996

EF1A1
Elongation factor 1-alpha 1

1

2

High-throughput

0.479

High

595997

EWS
RNA-binding protein EWS

1

2

High-throughput

0.479

High

596001

LG3BP
Galectin-3-binding protein

1

4

High-throughput

0.479

High

596005

TBA1A
Tubulin alpha-1A chain

1

11

High-throughput

0.479

High

596006

CCD25
Coiled-coil domain-containing protein 25

1

1

High-throughput

0.479

High

596007

HORN
Hornerin

1

2

High-throughput

0.479

High

596023

FLRT3
Leucine-rich repeat transmembrane protein FLRT3

1

1

High-throughput

0.479

High

596025

LOXL2
Lysyl oxidase homolog 2

1

8

High-throughput

0.479

High

596026

HYOU1
Hypoxia up-regulated protein 1

1

3

High-throughput

0.479

High

133878

DDX3X
ATP-dependent RNA helicase DDX3X

1

0

High-throughput

0.458

High

417150

ENOA
Alpha-enolase

1

0

High-throughput

0.458

High

437265

4F2
Amino acid transporter heavy chain SLC3A2

1

0

High-throughput

0.458

High

595980

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.458

High

596011

OR6T1
Olfactory receptor 6T1

1

0

High-throughput

0.458

High

596013

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

596020

DHX33
ATP-dependent RNA helicase DHX33

1

0

High-throughput

0.458

High

129889

PLOD2
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2

1

6

High-throughput

0.437

High

359302

K1C14
Keratin, type I cytoskeletal 14

1

20

High-throughput

0.437

High

359465

K2C6A
Keratin, type II cytoskeletal 6A

1

20

High-throughput

0.437

High

380444

K2C6B
Keratin, type II cytoskeletal 6B

1

20

High-throughput

0.437

High

445004

K1C16
Keratin, type I cytoskeletal 16

1

20

High-throughput

0.437

High

502903

MYH3
Myosin-3

1

2

High-throughput

0.437

High

522537

MYH1
Myosin-1

1

2

High-throughput

0.437

High

522589

MYH7
Myosin-7

1

2

High-throughput

0.437

High

531320

K1C10
Keratin, type I cytoskeletal 10

1

20

High-throughput

0.437

High

531533

K2C5
Keratin, type II cytoskeletal 5

1

20

High-throughput

0.437

High

535325

GFAP
Glial fibrillary acidic protein

1

20

High-throughput

0.437

High

595972

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

595977

RL12
Large ribosomal subunit protein uL11

1

2

High-throughput

0.437

High

595978

K1C9
Keratin, type I cytoskeletal 9

1

20

High-throughput

0.437

High

595979

K22E
Keratin, type II cytoskeletal 2 epidermal

1

20

High-throughput

0.437

High

595981

K2C6C
Keratin, type II cytoskeletal 6C

1

20

High-throughput

0.437

High

595990

RS4X
Small ribosomal subunit protein eS4, X isoform

1

1

High-throughput

0.437

High

595991

ACTA
Actin, aortic smooth muscle

1

3

High-throughput

0.437

High

595994

RL30
Large ribosomal subunit protein eL30

1

2

High-throughput

0.437

High

595998

PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

1

6

High-throughput

0.437

High

596000

K1C17
Keratin, type I cytoskeletal 17

1

20

High-throughput

0.437

High

596002

K1H1
Keratin, type I cuticular Ha1

1

20

High-throughput

0.437

High

596009

GT251
Procollagen galactosyltransferase 1

1

6

High-throughput

0.437

High

596016

ARHGH
Rho guanine nucleotide exchange factor 17

1

2

High-throughput

0.437

High

596017

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

2

High-throughput

0.437

High

596018

TBB6
Tubulin beta-6 chain

1

14

High-throughput

0.437

High

596022

KCTD5
BTB/POZ domain-containing protein KCTD5

1

2

High-throughput

0.437

High

596024

TGRM1
TOG array regulator of axonemal microtubules protein 1

1

1

High-throughput

0.437

High

596027

SNX13
Sorting nexin-13

1

4

High-throughput

0.437

High

595971

EF1G
Elongation factor 1-gamma

1

0

High-throughput

0.282

High

595986

HUNK
Hormonally up-regulated neu tumor-associated kinase

1

0

High-throughput

0.282

High

596015

CLP1L
Lipid scramblase CLPTM1L

1

0

High-throughput

0.269

Low

176380

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

0

Small-scale

0.261

Low

180005

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

0

High-throughput

0.249

Low

417070

KCRM
Creatine kinase M-type

1

0

High-throughput

0.249

Low

595988

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.249

Low

595992

VISL1
Visinin-like protein 1

1

0

High-throughput

0.249

Low

595999

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.249

Low

596003

EXOS6
Exosome complex component MTR3

1

0

High-throughput

0.249

Low

596004

KAZRN
Kazrin

1

0

High-throughput

0.249

Low

596010

SMG8
Nonsense-mediated mRNA decay factor SMG8

1

0

High-throughput

0.249

Low

596012

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.249

Low

596019

TM109
Voltage-gated monoatomic cation channel TMEM109

1

0

High-throughput

0.249

Low

595989

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.238

Low

596008

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

Small-scale

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024