HitPredict

Interactor 1: CCR7 (P32248)
C-C chemokine receptor type 7 (C-C CKR-7) (CC-CKR-7) (CCR-7) (BLR2) (CDw197) (Epstein-Barr virus-induced G-protein coupled receptor 1) (EBI1) (EBV-induced G-protein coupled receptor 1) (MIP-3 beta receptor) (CD antigen CD197)
Gene: CCR7

Interactor 2: CCL19 (Q99731)
C-C motif chemokine 19 (Beta-chemokine exodus-3) (CK beta-11) (Epstein-Barr virus-induced molecule 1 ligand chemokine) (EBI1 ligand chemokine) (ELC) (Macrophage inflammatory protein 3 beta) (MIP-3-beta) (Small-inducible cytokine A19)
Gene: CCL19

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.866

The method score is based on:

Property Details
Experiments 9153236, 9507024, 15546958
Identification Methods pull down, biophysical, biochemical, saturation binding, competition binding
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~IL8
Common GO terms GO:0001768 - establishment of T cell polarity
GO:0002407 - dendritic cell chemotaxis
GO:0002408 - myeloid dendritic cell chemotaxis
GO:0002606 - positive regulation of dendritic cell antigen processing and presentation
GO:0006954 - inflammatory response
and 15 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 378
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024