Interactor 1: P5CR1 (P32322)
Pyrroline-5-carboxylate reductase 1, mitochondrial (P5C reductase 1) (P5CR 1) (EC 1.5.1.2)
Gene: PYCR1
Interactor 2: PARK7 (Q99497)
Parkinson disease protein 7 (Maillard deglycase) (Oncogene DJ1) (Parkinsonism-associated deglycase) (Protein DJ-1) (DJ-1) (Protein/nucleic acid deglycase DJ-1) (EC 3.1.2.-, EC 3.5.1.-, EC 3.5.1.124)
Gene: PARK7
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 0.55 | 0.512 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23743200 |
| Identification Methods | anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005739 - mitochondrion GO:0005759 - mitochondrial matrix GO:0034599 - cellular response to oxidative stress GO:0051881 - regulation of mitochondrial membrane potential GO:1903377 - negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
