HitPredict

Interactor 1: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: DC2I1 (Q8WVS4)
Cytoplasmic dynein 2 intermediate chain 1 (Dynein 2 intermediate chain 1) (WD repeat-containing protein 60)
Gene: DYNC2I1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	32867128
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 215 Hs			1 1066
+	Hs
		157285 SSRP1_HUMAN (53-164): 1.6e-28: 114: 37.50		CTRO_HUMAN (13-607): 7.84e-39: 160: 10.13
+	Hs
		659245 SP100_HUMAN (25-178): 7.58e-34: 129: 87.66		NIPBL_HUMAN (2-453): 5.76e-32: 138: 16.96
+	Hs
		157082 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		CTRO_HUMAN (13-607): 7.84e-39: 160: 10.13
+	Hs
		1065244 SSRP1_HUMAN (53-164): 1.6e-28: 114: 37.50		NIPBL_HUMAN (2-453): 5.76e-32: 138: 16.96
+	Hs
		687238 HMGB2_HUMAN (1-187): 7.94e-42: 142: 82.89		EIF3A_HUMAN (12-555): 3.21e-23: 108: 11.55
+	Hs
		872435 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		NIPBL_HUMAN (2-453): 5.76e-32: 138: 16.96
+	Hs
		1065190 SSRP1_HUMAN (53-164): 1.6e-28: 114: 37.50		EIF3A_HUMAN (12-555): 3.21e-23: 108: 11.55
+	Hs
		156930 UBF1_HUMAN (10-158): 4.17e-09: 57.8: 23.60		CTRO_HUMAN (13-607): 7.84e-39: 160: 10.13
+	Hs
		872662 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		MINT_HUMAN (15-596): 2.53e-23: 109: 10.49
+	Hs
		872598 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		EVPL_HUMAN (1-640): 3.32e-21: 102: 9.38
+	Hs
		1065251 SSRP1_HUMAN (53-164): 1.6e-28: 114: 37.50		ANR11_HUMAN (2-581): 6.99e-13: 75.5: 11.22
+	Hs
		587588 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		DESP_HUMAN (6-576): 1.58e-15: 84.3: 11.67
+	Ce
		1067135 HMGBH_CAEEL (2-82): 1.86e-10: 60.5: 32.10		Q20641_CAEEL (4-605): 9.65e-27: 120: 13.82
+	Mm
		98057 SOX17_MOUSE (4-90): 4.12e-22: 94.8: 18.39		DESP_MOUSE (16-599): 9.07e-16: 85.1: 9.52
+	Hs
		1121850 CIC_HUMAN (3-96): 6.88e-12: 65.9: 22.34		EIF3A_HUMAN (12-555): 3.21e-23: 108: 11.55
+	Hs
		872548 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		BD1L1_HUMAN (4-605): 3.04e-12: 73.5: 10.02
+	Hs
		872193 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		MAP1A_HUMAN (3-399): 7.51e-12: 72.2: 11.61
+	Hs
		587777 CIC_HUMAN (3-96): 6.88e-12: 65.9: 22.34		DESP_HUMAN (6-576): 1.58e-15: 84.3: 11.67
+	Hs
		1341003 CIC_HUMAN (3-96): 6.88e-12: 65.9: 22.34		THOC2_HUMAN (11-404): 9.74e-10: 65.3: 12.62
+	Hs
		551603 UBF1_HUMAN (10-158): 4.17e-09: 57.8: 23.60		NFH_HUMAN (2-454): 3.48e-12: 73: 12.55