HitPredict

Interactor 1: STH1 (P32597)
Nuclear protein STH1/NPS1 (EC 3.6.4.12) (ATP-dependent helicase STH1) (Chromatin structure-remodeling complex protein STH1) (SNF2 homolog)
Gene: STH1

Interactor 2: H2AZ (Q12692)
Histone H2A.Z
Gene: HTZ1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	37968396, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0006338 - chromatin remodeling GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1359 Sc			1 134
+	Sc
		392357 STH1_YEAST (1-1359): 0: 950: 100.00		H2A2_YEAST (23-133): 1.36e-51: 161: 62.50
+	Sc
		392052 SNF2_YEAST (19-1357): 0: 733: 42.05		H2A1_YEAST (23-133): 7.94e-52: 162: 62.50
+	Sc
		392293 SNF2_YEAST (19-1357): 0: 733: 42.05		H2A2_YEAST (23-133): 1.36e-51: 161: 62.50
+	Sc
		996427 ISW2_YEAST (334-991): 0: 684: 39.40		H2AZ_YEAST (1-134): 2.81e-53: 165: 100.00
+	Sc
		392595 ISW2_YEAST (334-991): 0: 684: 39.40		H2A2_YEAST (23-133): 1.36e-51: 161: 62.50
+	Hs
		470170 CHD8_HUMAN (78-1202): 0: 683: 22.67		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		391728 CHD9_HUMAN (80-1211): 0: 691: 23.01		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Hs
		229433 SMCA5_HUMAN (366-1266): 0: 634: 30.99		H2A2B_HUMAN (7-129): 3.24e-52: 162: 56.45
+	Hs
		1018640 CHD3_HUMAN (295-1281): 0: 630: 25.58		H2A1H_HUMAN (7-133): 5.62e-52: 162: 55.47
+	Hs
		391915 CHD8_HUMAN (78-1202): 0: 683: 22.67		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Hs
		1059647 CHD4_HUMAN (295-1253): 0: 614: 25.95		H2A2C_HUMAN (7-134): 6.76e-52: 162: 55.04
+	Hs
		1059717 CHD4_HUMAN (295-1253): 0: 614: 25.95		H2A2B_HUMAN (7-129): 3.24e-52: 162: 56.45
+	Hs
		1059795 CHD4_HUMAN (295-1253): 0: 614: 25.95		H2A1H_HUMAN (7-133): 5.62e-52: 162: 55.47
+	Hs
		229286 SMCA5_HUMAN (366-1266): 0: 634: 30.99		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		469951 SMCA1_HUMAN (377-1266): 0: 631: 31.07		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		470021 CHD4_HUMAN (295-1253): 0: 614: 25.95		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		229279 SMCA5_HUMAN (366-1266): 0: 634: 30.99		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Hs
		391675 CHD3_HUMAN (295-1281): 0: 630: 25.58		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Hs
		391704 CHD4_HUMAN (295-1253): 0: 614: 25.95		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Sc
		392106 ISW1_YEAST (439-958): 1.81e-120: 405: 46.07		H2A1_YEAST (23-133): 7.94e-52: 162: 62.50