HitPredict

Interactor 1: BRR2 (P32639)
Pre-mRNA-splicing helicase BRR2 (EC 3.6.4.13) (Protein Snu246)
Gene: BRR2

Interactor 2: RU17 (Q00916)
U1 small nuclear ribonucleoprotein 70 kDa homolog (U1 70K) (U1 snRNP 70 kDa homolog) (U1-70K) (U1 small nuclear ribonucleoprotein SNP1) (U1 snRNP protein SNP1)
Gene: SNP1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	11290703, 9207794
Identification Methods	two hybrid, coimmunoprecipitation, affinity chromatography technology
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005681 - spliceosomal complex
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 2163 Sc			1 300
+	Hs
		272012 U520_HUMAN (16-2163): 0: 1597: 38.84		RU17_HUMAN (8-237): 2.03e-40: 147: 30.00
+	Sc
		376698 BRR2_YEAST (1-2163): 0: 1534: 100.00		PABP_YEAST (75-258): 9.92e-21: 94.1: 16.30
+	Hs
		516589 ASCC3_HUMAN (65-2162): 0: 1382: 31.01		PABP1_HUMAN (99-262): 8.85e-27: 111: 17.68
+	Sp
		678721 BRR2_SCHPO (5-2162): 0: 1396: 41.00		PABP_SCHPO (34-258): 4.76e-21: 94.9: 13.78
+	Sp
		142975 YE02_SCHPO (377-925): 4.47e-87: 311: 21.59		RU17_SCHPO (7-267): 1.87e-50: 169: 34.48
+	Hs
		442361 DDX17_HUMAN (1345-1753): 1.1e-96: 332: 11.35		RU17_HUMAN (8-237): 2.03e-40: 147: 30.00
+	Hs
		441866 DDX5_HUMAN (1344-1752): 6.23e-93: 317: 11.35		RU17_HUMAN (8-237): 2.03e-40: 147: 30.00
+	Hs
		1048159 DDX17_HUMAN (1345-1753): 1.1e-96: 332: 11.35		HNRPD_HUMAN (72-194): 9.95e-30: 117: 24.00
+	Mm
		857323 DDX17_MOUSE (1345-1753): 1.48e-97: 332: 11.35		TIA1_MOUSE (102-299): 4.92e-27: 110: 11.57
+	Hs
		442449 DDX23_HUMAN (1275-1768): 3.27e-82: 292: 13.30		RU17_HUMAN (8-237): 2.03e-40: 147: 30.00
+	Hs
		571427 DDX5_HUMAN (1344-1752): 6.23e-93: 317: 11.35		ROA0_HUMAN (102-296): 3.63e-28: 112: 17.35
+	Mm
		857351 Q8BTS0_MOUSE (1344-1752): 8.2e-93: 317: 11.35		TIA1_MOUSE (102-299): 4.92e-27: 110: 11.57
+	Hs
		441927 MTREX_HUMAN (355-1000): 4.3e-76: 278: 18.12		RU17_HUMAN (8-237): 2.03e-40: 147: 30.00
+	Sc
		376837 MTR4_YEAST (364-927): 1.48e-92: 329: 20.07		PABP_YEAST (75-258): 9.92e-21: 94.1: 16.30
+	Mm
		936480 DDX5_MOUSE (1344-1752): 3.8e-93: 318: 11.35		TIAR_MOUSE (101-297): 3.52e-23: 99: 13.15
+	Sp
		143097 YE02_SCHPO (377-925): 4.47e-87: 311: 21.59		PABP_SCHPO (34-258): 4.76e-21: 94.9: 13.78
+	Hs
		442160 DHX8_HUMAN (1353-1741): 3.82e-48: 191: 11.31		RU17_HUMAN (8-237): 2.03e-40: 147: 30.00