Protein: LRC8C
Volume-regulated anion channel subunit LRRC8C (Factor for adipocyte differentiation 158) (Leucine-rich repeat-containing protein 8C)

Gene: LRC8C, LRRC8C
Organism: Homo sapiens
Interactions: 33
UniProt ID: Q8TDW0

Gene Ontology (top 5):
GO:0005225 - volume-sensitive anion channel activity
GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0015734 - taurine transmembrane transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1243375

LRC8B
Volume-regulated anion channel subunit LRRC8B

4

13

High-throughput

0.892

High

1310828

LRC8A
Volume-regulated anion channel subunit LRRC8A

2

18

Small-scale

0.754

High

127378

LEG8
Galectin-8

3

6

High-throughput

0.667

High

1192265

ZACN
Ligand-gated cation channel ZACN

3

9

High-throughput

0.667

High

268931

FCG3B
Low affinity immunoglobulin gamma Fc region receptor III-B

3

3

High-throughput

0.656

High

669038

FPR2
N-formyl peptide receptor 2

2

11

High-throughput

0.628

High

855361

5HT3A
5-hydroxytryptamine receptor 3A

2

9

High-throughput

0.628

High

601384

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

1351774

POPD2
Popeye domain-containing protein 2

2

1

High-throughput

0.611

High

1307711

CILP2
Cartilage intermediate layer protein 2

1

2

High-throughput

0.553

High

248492

O10H2
Olfactory receptor 10H2

1

5

High-throughput

0.536

High

349501

TSN15
Tetraspanin-15

1

3

High-throughput

0.536

High

595082

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

10

High-throughput

0.536

High

698930

CALX
Calnexin

1

4

High-throughput

0.536

High

938599

PSA
Puromycin-sensitive aminopeptidase

1

4

High-throughput

0.536

High

956952

CXCR4
C-X-C chemokine receptor type 4

1

6

High-throughput

0.536

High

1333575

SIDT2
SID1 transmembrane family member 2

1

3

High-throughput

0.536

High

1351773

TTYH1
Protein tweety homolog 1

1

4

High-throughput

0.536

High

1351776

HCST
Hematopoietic cell signal transducer

1

3

High-throughput

0.536

High

178968

SCAM2
Secretory carrier-associated membrane protein 2

1

0

High-throughput

0.513

High

1328485

M4A15
Membrane-spanning 4-domains subfamily A member 15

1

0

High-throughput

0.513

High

1351771

NCLN
BOS complex subunit NCLN

1

0

High-throughput

0.513

High

218523

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.479

High

242376

PRKN
E3 ubiquitin-protein ligase parkin

1

6

High-throughput

0.479

High

331177

KI20A
Kinesin-like protein KIF20A

1

9

High-throughput

0.479

High

1220689

RN123
E3 ubiquitin-protein ligase RNF123

1

3

High-throughput

0.479

High

1351775

OTULL
Inactive ubiquitin thioesterase OTULINL

1

3

High-throughput

0.479

High

616212

PGAM1
Phosphoglycerate mutase 1

1

0

High-throughput

0.458

High

1164198

UGPA
UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.458

High

1351772

IP3KC
Inositol-trisphosphate 3-kinase C

1

0

High-throughput

0.458

High

97131

E9PNY5
Fc gamma receptor IIIb

1

3

High-throughput

0.445

High

1187507

AR13B
ADP-ribosylation factor-like protein 13B

1

5

High-throughput

0.437

High

62776

XIRP2
Xin actin-binding repeat-containing protein 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025