HitPredict

Interactor 1: RAEP (P32864)
Rab proteins geranylgeranyltransferase component A (Rab escort protein) (REP)
Gene: MRS6

Interactor 2: YPT53 (P36019)
GTP-binding protein YPT53
Gene: YPT53

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.806

Property	Details
Experiments	11805837, 18719252
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 603 Sc			1 220
+	Sc
		350859 RAEP_YEAST (1-603): 0: 843: 100.00		YPT1_YEAST (10-218): 2.04e-87: 258: 29.67
+	Sc
		699419 RAEP_YEAST (1-603): 0: 843: 100.00		VPS21_YEAST (12-220): 3.21e-87: 258: 56.94
+	Sc
		699420 RAEP_YEAST (1-603): 0: 843: 100.00		YPT52_YEAST (11-179): 2.99e-54: 175: 53.13
+	Hs
		678333 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB13_HUMAN (6-208): 1.6e-87: 258: 31.03
+	Hs
		678344 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB1A_HUMAN (1-218): 9.59e-80: 239: 30.73
+	Mm
		838709 GDIA_MOUSE (45-434): 2.77e-176: 508: 25.76		RAB1A_MOUSE (1-218): 9.59e-80: 239: 30.73
+	Hs
		678343 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RB11A_HUMAN (1-219): 4.39e-79: 237: 32.58
+	Hs
		678394 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB1B_HUMAN (7-218): 2.87e-78: 235: 31.13
+	Hs
		678341 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB14_HUMAN (1-220): 7.04e-78: 234: 29.73
+	Hs
		678359 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RB11B_HUMAN (1-219): 5.78e-78: 234: 30.49
+	Hs
		592123 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB5A_HUMAN (14-196): 9.06e-57: 181: 53.26
+	Hs
		678330 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB5C_HUMAN (14-196): 2.33e-55: 177: 51.09
+	Hs
		592161 GDIB_HUMAN (45-434): 6.79e-174: 502: 26.26		RAB5A_HUMAN (14-196): 9.06e-57: 181: 53.26
+	Hs
		678339 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB5B_HUMAN (14-196): 1.86e-53: 172: 50.00
+	Hs
		678351 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB31_HUMAN (13-213): 4.21e-45: 150: 40.89
+	Hs
		678408 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RB22A_HUMAN (13-185): 2.29e-44: 148: 43.35
+	Hs
		592631 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB6A_HUMAN (9-220): 1.8e-42: 144: 36.32
+	Hs
		678407 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB21_HUMAN (12-220): 6.45e-40: 138: 34.93
+	Hs
		678402 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB6B_HUMAN (9-220): 1.5e-39: 136: 35.02
+	Hs
		678397 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB18_HUMAN (12-179): 5e-38: 132: 43.79