HitPredict

Interactor 1: RASK (P32883)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: Kras

Interactor 2: TSC1 (Q9EP53)
Hamartin (Tuberous sclerosis 1 protein homolog)
Gene: TSC1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0008283 - cell population proliferation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Mm			1 1161
+	Mm
		1142566 RASH_MOUSE (1-188): 3.11e-87: 256: 86.77		TSC1_MOUSE (1-1161): 0: 771: 100.00
+	Hs
		350408 RASK_HUMAN (1-189): 6.74e-78: 232: 98.94		TSC1_HUMAN (1-1161): 0: 767: 86.98
+	Hs
		349438 RASH_HUMAN (1-188): 3.11e-87: 256: 86.77		PHLB1_HUMAN (281-916): 3.43e-37: 154: 14.88
+	Hs
		348756 RASN_HUMAN (1-189): 3.17e-86: 253: 86.24		PHLB1_HUMAN (281-916): 3.43e-37: 154: 14.88
+	Hs
		350303 RASK_HUMAN (1-189): 6.74e-78: 232: 98.94		PHLB1_HUMAN (281-916): 3.43e-37: 154: 14.88
+	Hs
		254429 RASH_HUMAN (1-188): 3.11e-87: 256: 86.77		ROCK2_HUMAN (398-1090): 3.16e-25: 116: 12.76
+	Hs
		254428 RASN_HUMAN (1-189): 3.17e-86: 253: 86.24		ROCK2_HUMAN (398-1090): 3.16e-25: 116: 12.76
+	Hs
		349389 RASH_HUMAN (1-188): 3.11e-87: 256: 86.77		MRCKA_HUMAN (487-978): 2.97e-23: 109: 12.91
+	Hs
		348715 RASN_HUMAN (1-189): 3.17e-86: 253: 86.24		MRCKA_HUMAN (487-978): 2.97e-23: 109: 12.91
+	Hs
		1070238 RAB35_HUMAN (4-187): 2.06e-83: 246: 31.28		MRCKA_HUMAN (487-978): 2.97e-23: 109: 12.91
+	Hs
		349926 RASK_HUMAN (1-189): 6.74e-78: 232: 98.94		MYH9_HUMAN (649-1160): 1.28e-25: 117: 10.68
+	Hs
		254430 RASK_HUMAN (1-189): 6.74e-78: 232: 98.94		ROCK2_HUMAN (398-1090): 3.16e-25: 116: 12.76
+	Hs
		350237 RASK_HUMAN (1-189): 6.74e-78: 232: 98.94		MRCKA_HUMAN (487-978): 2.97e-23: 109: 12.91
+	Hs
		349030 RASN_HUMAN (1-189): 3.17e-86: 253: 86.24		MRCKB_HUMAN (421-862): 5.66e-16: 85.6: 11.45
+	Hs
		350413 RASK_HUMAN (1-189): 6.74e-78: 232: 98.94		MY18A_HUMAN (367-910): 1.36e-20: 101: 9.71
+	Hs
		1070480 RAB35_HUMAN (4-187): 2.06e-83: 246: 31.28		MRCKB_HUMAN (421-862): 5.66e-16: 85.6: 11.45
+	Hs
		349156 RASH_HUMAN (1-188): 3.11e-87: 256: 86.77		MYH10_HUMAN (617-910): 9.54e-10: 65.3: 13.27
+	Hs
		350729 RASK_HUMAN (1-189): 6.74e-78: 232: 98.94		MRCKB_HUMAN (421-862): 5.66e-16: 85.6: 11.45
+	Hs
		349927 RASK_HUMAN (1-189): 6.74e-78: 232: 98.94		MYH10_HUMAN (617-910): 9.54e-10: 65.3: 13.27
+	Hs
		350457 RASK_HUMAN (1-189): 6.74e-78: 232: 98.94		KI16B_HUMAN (692-962): 9.32e-09: 62.1: 14.77