HitPredict

Interactor 1: ELK4 (P28324)
ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1) (SRF accessory protein 1)
Gene: ELK4

Interactor 2: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34535262
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 431 Hs			1 526
+	Hs
		1030970 FLI1_HUMAN (3-156): 1.27e-34: 135: 33.33		RBP56_HUMAN (42-460): 2.96e-42: 161: 48.10
+	Hs
		775019 FLI1_HUMAN (3-156): 1.27e-34: 135: 33.33		FUS_HUMAN (1-526): 5.12e-39: 150: 100.00
+	Hs
		578294 ETS2_HUMAN (3-107): 8.12e-42: 155: 49.06		EWS_HUMAN (3-451): 4.67e-30: 126: 31.05
+	Hs
		622441 ELK1_HUMAN (1-430): 1.68e-37: 143: 31.17		EWS_HUMAN (3-451): 4.67e-30: 126: 31.05
+	Hs
		702345 ELK4_HUMAN (1-431): 5.25e-56: 193: 100.00		PABP4_HUMAN (280-379): 4.84e-13: 73.5: 22.00
+	Hs
		1030953 FLI1_HUMAN (3-156): 1.27e-34: 135: 33.33		EWS_HUMAN (3-451): 4.67e-30: 126: 31.05
+	Hs
		832509 ETV3_HUMAN (4-410): 7.5e-34: 134: 20.59		EWS_HUMAN (3-451): 4.67e-30: 126: 31.05
+	Hs
		1008542 ELF3_HUMAN (5-89): 4.84e-33: 129: 42.53		EWS_HUMAN (3-451): 4.67e-30: 126: 31.05