Interactor 1: SYEP (P28668)
Bifunctional glutamate/proline--tRNA ligase (Bifunctional aminoacyl-tRNA synthetase) [Includes: Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase); Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)]
Gene: GluProRS

Interactor 2: SYQ (Q9Y105)
Probable glutamine--tRNA ligase (EC 6.1.1.18) (Glutaminyl-tRNA synthetase)
Gene: GlnRS

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 22036573, 38944040
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains tRNA-synt_1c~tRNA-synt_1c, tRNA-synt_1c~tRNA-synt_1c_C, tRNA-synt_1c~tRNA-synt_1c_C2, tRNA-synt_1c~tRNA_synt_1c_R2, tRNA-synt_1c_C~tRNA-synt_1c_C, tRNA-synt_1c_C~tRNA-synt_1c_C2
Common GO terms GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0017101 - aminoacyl-tRNA synthetase multienzyme complex
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 1714
Dm

1 778
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Sc
+ Tt

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Last updated: 11Aug2025