Interactor 1: CBF5 (P33322)
H/ACA ribonucleoprotein complex subunit CBF5 (EC 5.4.99.-) (Centromere-binding factor 5) (Centromere/microtubule-binding protein CBF5) (H/ACA snoRNP protein CBF5) (Small nucleolar RNP protein CBF5) (p64')
Gene: CBF5

Interactor 2: NOP10 (Q6Q547)
H/ACA ribonucleoprotein complex subunit NOP10 (Nucleolar protein 10) (Nucleolar protein family A member 3) (snoRNP protein NOP10)
Gene: NOP10

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.955

The method score is based on:

Property Details
Experiments 12242285, 37968396, 15388873, 21558325, 22085967, 22117216
Identification Methods coimmunoprecipitation, affinity chromatography technology, pull down, isothermal titration calorimetry, cross-linking study, x-ray crystallography
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains DKCLD~Nop10p, Nop10p~TruB_C_2, Nop10p~TruB_N
Common GO terms GO:0000454 - snoRNA guided rRNA pseudouridine synthesis
GO:0006364 - rRNA processing
GO:0031118 - rRNA pseudouridine synthesis
GO:0031120 - snRNA pseudouridine synthesis
GO:0031429 - box H/ACA snoRNP complex
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 483
Sc

1 58
+ Rn
+ Hs

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Last updated: 15 Jul 2024