HitPredict

Interactor 1: RXRA (P28700)
Retinoic acid receptor RXR-alpha (Nuclear receptor subfamily 2 group B member 1) (Retinoid X receptor alpha)
Gene: RXRA

Interactor 2: SQSTM (Q64337)
Sequestosome-1 (STONE14) (Ubiquitin-binding protein p62)
Gene: Sqstm1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	27728806
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005739 - mitochondrion GO:0008270 - zinc ion binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 467 Mm			1 442
+	Hs
		625809 RXRA_HUMAN (1-467): 1.6e-177: 507: 97.43		SQSTM_HUMAN (1-442): 0: 715: 89.82
+	Hs
		396053 ESR1_HUMAN (1-464): 8.8e-114: 349: 23.56		SQSTM_HUMAN (1-442): 0: 715: 89.82
+	Hs
		520572 RARA_HUMAN (48-462): 3.26e-112: 340: 28.67		SQSTM_HUMAN (1-442): 0: 715: 89.82
+	Hs
		652510 NR4A1_HUMAN (3-460): 5.12e-106: 329: 27.37		SQSTM_HUMAN (1-442): 0: 715: 89.82
+	Hs
		1107983 ESR2_HUMAN (15-463): 4.54e-106: 327: 25.31		SQSTM_HUMAN (1-442): 0: 715: 89.82
+	Hs
		1295516 ESR2_HUMAN (15-463): 4.54e-106: 327: 25.31		MIB1_HUMAN (105-228): 1.66e-27: 117: 27.69
+	Hs
		342717 ESR1_HUMAN (1-464): 8.8e-114: 349: 23.56		HERC2_HUMAN (120-197): 1.36e-11: 69: 32.50
+	Hs
		342990 ESR2_HUMAN (15-463): 4.54e-106: 327: 25.31		HERC2_HUMAN (120-197): 1.36e-11: 69: 32.50