HitPredict

Interactor 1: S10A2 (P29034)
Protein S100-A2 (CAN19) (Protein S-100L) (S100 calcium-binding protein A2)
Gene: S100A2

Interactor 2: TRPM4 (Q8TD43)
Transient receptor potential cation channel subfamily M member 4 (hTRPM4) (Calcium-activated non-selective cation channel 1) (Long transient receptor potential channel 4) (LTrpC-4) (LTrpC4) (Melastatin-4)
Gene: TRPM4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	31837246
Identification Methods	fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 98 Hs			1 1214
+	Hs
		657040 S10A1_HUMAN (2-91): 3.93e-38: 124: 52.22		TRPM4_HUMAN (1-1214): 0: 1238: 100.00
+	Hs
		686844 S10A4_HUMAN (2-97): 3.37e-38: 124: 61.46		TRPM4_HUMAN (1-1214): 0: 1238: 100.00
+	Hs
		731781 S10AB_HUMAN (2-97): 2.19e-37: 123: 29.90		TRPM4_HUMAN (1-1214): 0: 1238: 100.00
+	Hs
		754584 S10A3_HUMAN (2-98): 2.61e-36: 120: 43.30		TRPM4_HUMAN (1-1214): 0: 1238: 100.00
+	Hs
		682556 S100P_HUMAN (4-92): 1.21e-35: 118: 42.70		TRPM4_HUMAN (1-1214): 0: 1238: 100.00
+	Hs
		954976 S10AA_HUMAN (2-91): 2.63e-33: 112: 36.67		TRPM4_HUMAN (1-1214): 0: 1238: 100.00
+	Hs
		407666 S100B_HUMAN (4-92): 9.17e-33: 111: 44.94		TRPM4_HUMAN (1-1214): 0: 1238: 100.00
+	Hs
		445033 S10A9_HUMAN (4-98): 2.66e-30: 105: 32.29		TRPM4_HUMAN (1-1214): 0: 1238: 100.00
+	Hs
		445224 S10A6_HUMAN (2-93): 2.21e-30: 104: 46.74		TRPM4_HUMAN (1-1214): 0: 1238: 100.00
+	Hs
		424229 S10A8_HUMAN (2-89): 1.07e-26: 95.7: 29.55		TRPM4_HUMAN (1-1214): 0: 1238: 100.00
+	Hs
		754554 S10A5_HUMAN (2-91): 6.66e-26: 93.4: 53.33		TRPM4_HUMAN (1-1214): 0: 1238: 100.00
+	Hs
		1350775 S10AE_HUMAN (4-85): 1.24e-21: 83: 25.61		TRPM4_HUMAN (1-1214): 0: 1238: 100.00