HitPredict

Interactor 1: GCN1 (P33892)
eIF-2-alpha kinase activator GCN1 (General control non-derepressible protein 1) (Translational activator GCN1)
Gene: GCN1

Interactor 2: IMB4 (P40069)
Importin subunit beta-4 (Importin-123) (Karyopherin subunit beta-4) (Karyopherin-123) (Ran-binding protein YRB4)
Gene: KAP123

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	16429126, 37968396
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 2672 Sc			1 1113
+	Sc
		687918 GCN1_YEAST (1-2672): 0: 1798: 100.00		IMB3_YEAST (5-1065): 1.11e-110: 372: 17.51
+	Sc
		707936 GCN1_YEAST (1-2672): 0: 1798: 100.00		IMB1_YEAST (6-696): 1.11e-36: 151: 13.31
+	Zm
		24385 A0A1D6IHP1_MAIZE (877-1759): 3.34e-20: 100: 13.72		A0A1D6IHP1_MAIZE (3-1093): 3.29e-167: 525: 18.99
+	Dm
		1369716 CAND1_DROME (808-2002): 4.48e-21: 104: 10.33		Q9VN44_DROME (1-1105): 5.9e-160: 505: 17.70
+	Sp
		251579 2AAA_SCHPO (1640-2239): 9.32e-33: 138: 12.92		IMB3_SCHPO (5-1102): 4.33e-144: 463: 16.89
+	Sp
		223897 2AAA_SCHPO (1640-2239): 9.32e-33: 138: 12.92		IMB4_SCHPO (1-1112): 9.95e-141: 453: 29.71
+	Hs
		1201969 CAND1_HUMAN (814-1469): 2.62e-09: 65.1: 13.54		CAND1_HUMAN (1-1112): 1.78e-93: 327: 11.03
+	Hs
		1060859 TNPO1_HUMAN (2073-2625): 4.61e-13: 77.5: 11.45		IMB1_HUMAN (336-1075): 4.67e-46: 181: 11.11
+	Hs
		155576 TNPO2_HUMAN (2197-2581): 2.64e-10: 68.2: 12.16		IMB1_HUMAN (336-1075): 4.67e-46: 181: 11.11
+	Hs
		1060811 CAND1_HUMAN (814-1469): 2.62e-09: 65.1: 13.54		IMB1_HUMAN (336-1075): 4.67e-46: 181: 11.11