Interactor 1: MCM4 (P33991)
DNA replication licensing factor MCM4 (EC 3.6.4.12) (CDC21 homolog) (P1-CDC21)
Gene: MCM4

Interactor 2: MCM7 (P33993)
DNA replication licensing factor MCM7 (EC 3.6.4.12) (CDC47 homolog) (P1.1-MCM3)
Gene: MCM7

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 12694531, 8798650, 35235311, 37071682, 27173435, 17296731, 9099751, 12207017, 15232106, 24299456, 23764002, 12364596, 22540012
Identification Methods pull down, affinity chromatography technology, cross-linking study, tandem affinity purification, anti bait coimmunoprecipitation, protein array, coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~MCM, MCM~MCM_lid, MCM~MCM_N, MCM~MCM_OB, MCM_N~MCM_N, MCM_N~MCM_OB, MCM_OB~MCM_OB
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0000781 - chromosome, telomeric region
GO:0003697 - single-stranded DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 10 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 863
Hs

1 719
+ Xl
+ Hs
+ Hs
+ Hs
+ Xl
+ Dm
+ Hs
+ Xl
+ Xl
+ Xl
+ Xl
+ Dm
+ Dm
+ Dm
+ Hs
+ Xl
+ Xl
+ At

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Last updated: 15 Jul 2024