HitPredict

Interactor 1: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Interactor 2: TTC1 (Q99614)
Tetratricopeptide repeat protein 1 (TPR repeat protein 1)
Gene: TTC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	14503850
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0006457 - protein folding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 840 Hs			1 292
+	Hs
		714212 HSP74_HUMAN (1-840): 0: 993: 100.00		FKBP5_HUMAN (5-273): 9.22e-47: 164: 17.20
+	Hs
		320901 HS74L_HUMAN (1-840): 0: 959: 63.21		TTC1_HUMAN (1-292): 1.2e-60: 196: 100.00
+	Hs
		714190 HSP74_HUMAN (1-840): 0: 993: 100.00		FKBP4_HUMAN (29-282): 8.06e-45: 159: 18.02
+	Hs
		714418 HSP74_HUMAN (1-840): 0: 993: 100.00		RPAP3_HUMAN (72-252): 7.36e-41: 151: 24.86
+	Hs
		714148 HSP74_HUMAN (1-840): 0: 993: 100.00		PPP5_HUMAN (91-287): 1.25e-38: 143: 23.23
+	Hs
		213491 HSP74_HUMAN (1-840): 0: 993: 100.00		SGTA_HUMAN (39-204): 5.37e-14: 73: 13.25
+	Hs
		714375 HSP74_HUMAN (1-840): 0: 993: 100.00		DNJC7_HUMAN (120-221): 1.37e-11: 66.6: 37.26
+	Hs
		213427 HS74L_HUMAN (1-840): 0: 959: 63.21		SGTA_HUMAN (39-204): 5.37e-14: 73: 13.25
+	Hs
		320902 HS74L_HUMAN (1-840): 0: 959: 63.21		DNJC7_HUMAN (120-221): 1.37e-11: 66.6: 37.26
+	Hs
		1267736 HS105_HUMAN (1-840): 0: 938: 62.95		DNJC7_HUMAN (120-221): 1.37e-11: 66.6: 37.26
+	Ce
		108031 HSP1_CAEEL (2-603): 0: 811: 31.48		G5EG62_CAEEL (109-271): 6.06e-45: 164: 28.22
+	At
		612321 HS701_ARATH (2-604): 0: 815: 32.57		OE64C_ARATH (59-234): 8.76e-40: 148: 25.57
+	At
		99225 HS701_ARATH (2-604): 0: 815: 32.57		OE64M_ARATH (59-236): 1.4e-36: 139: 26.40
+	Ce
		183700 HSP1_CAEEL (2-603): 0: 811: 31.48		STIP1_CAEEL (114-275): 9.18e-15: 75.1: 21.71
+	Sc
		695109 HSP7F_YEAST (5-697): 5.7e-137: 424: 37.61		PPT1_YEAST (106-254): 1.71e-39: 146: 28.86
+	Hs
		503930 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		FKBP4_HUMAN (29-282): 8.06e-45: 159: 18.02
+	Hs
		503738 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		PPP5_HUMAN (91-287): 1.25e-38: 143: 23.23
+	Hs
		503968 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		PPID_HUMAN (19-251): 1.93e-37: 138: 17.07
+	Hs
		297027 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		TOM70_HUMAN (120-215): 6.68e-14: 73.6: 39.58
+	Hs
		213468 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		SGTA_HUMAN (39-204): 5.37e-14: 73: 13.25