HitPredict

Interactor 1: B3KSH4 (B3KSH4)
Huntingtin interacting protein 2, isoform CRA_a (cDNA FLJ36214 fis, clone THYMU2000672, highly similar to Ubiquitin-conjugating enzyme E2-25 kDa)
Gene: HIP2

Interactor 2: TRIM2 (Q9C040)
Tripartite motif-containing protein 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM2) (RING finger protein 86) (RING-type E3 ubiquitin transferase TRIM2)
Gene: TRIM2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	19549727
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 97 Hs			1 744
+	Hs
		896371 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		TRIM2_HUMAN (1-744): 0: 649: 100.00
+	Hs
		262167 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		TRIM3_HUMAN (1-744): 0: 607: 65.86
+	Hs
		896381 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		TRI39_HUMAN (14-490): 4.43e-91: 296: 15.96
+	Hs
		584923 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		RO52_HUMAN (8-498): 1.12e-95: 306: 16.17
+	Hs
		72168 B3KSH4_HUMAN (1-97): 7.05e-34: 113: 100.00		TRI39_HUMAN (14-490): 4.43e-91: 296: 15.96
+	Hs
		536773 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		TRI27_HUMAN (8-509): 4.56e-84: 277: 13.11
+	Hs
		72135 B3KSH4_HUMAN (1-97): 7.05e-34: 113: 100.00		TRI27_HUMAN (8-509): 4.56e-84: 277: 13.11
+	Hs
		896370 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		TRIM5_HUMAN (10-497): 3.15e-81: 269: 14.26
+	Mm
		919925 UB2D2_MOUSE (1-51): 4.95e-30: 105: 39.22		TRI17_MOUSE (8-490): 1.87e-85: 280: 12.13
+	Hs
		536779 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		TRI27_HUMAN (8-509): 4.56e-84: 277: 13.11
+	Hs
		72161 B3KSH4_HUMAN (1-97): 7.05e-34: 113: 100.00		TRIM5_HUMAN (10-497): 3.15e-81: 269: 14.26
+	Hs
		896330 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		TRI50_HUMAN (8-485): 1.62e-74: 251: 14.55
+	Hs
		135019 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		TRI38_HUMAN (8-484): 8.26e-78: 259: 14.69
+	Hs
		175659 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		TRI18_HUMAN (15-449): 2.83e-65: 230: 16.51
+	Hs
		72133 B3KSH4_HUMAN (1-97): 7.05e-34: 113: 100.00		TRI18_HUMAN (15-449): 2.83e-65: 230: 16.51
+	Hs
		175664 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		TRI18_HUMAN (15-449): 2.83e-65: 230: 16.51
+	Hs
		896345 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		TRI63_HUMAN (13-283): 2.14e-62: 214: 21.95
+	Hs
		242838 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		TRI13_HUMAN (15-309): 1.69e-55: 197: 21.59
+	Ce
		977012 Q9TZ69_CAEEL (1-96): 9.68e-41: 134: 42.71		NHL1_CAEEL (573-742): 4.1e-33: 139: 35.63
+	Ce
		715104 UBC2_CAEEL (1-51): 5.95e-30: 105: 41.18		NHL1_CAEEL (573-742): 4.1e-33: 139: 35.63