HitPredict

Interactor 1: SPT7 (P35177)
Transcriptional activator SPT7
Gene: SPT7

Interactor 2: GLE2 (P40066)
mRNA export factor GLE2 (Nuclear pore protein GLE2) (Nucleoporin GLE2) (poly(A) RNA export protein RAE1)
Gene: GLE2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	21734642
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1332 Sc			1 365
+	Hs
		211219 PHIP_HUMAN (234-918): 2.13e-75: 278: 12.26		BUB3_HUMAN (26-363): 4.13e-92: 280: 33.63
+	Hs
		211254 BRD7_HUMAN (341-931): 1.06e-58: 217: 12.89		BUB3_HUMAN (26-363): 4.13e-92: 280: 33.63
+	Hs
		943875 KAT2A_HUMAN (429-536): 2.27e-34: 144: 26.85		RAE1L_HUMAN (1-365): 8.11e-95: 288: 40.27
+	Mm
		1207958 KAT2A_MOUSE (429-536): 2.21e-34: 144: 26.85		RAE1L_MOUSE (16-365): 1.23e-92: 283: 40.34
+	Hs
		1346965 BAZ2A_HUMAN (149-547): 4.67e-72: 268: 15.57		NLE1_HUMAN (214-363): 1.04e-26: 112: 11.92
+	Hs
		1346964 BAZ2B_HUMAN (134-547): 2.87e-69: 259: 18.52		NLE1_HUMAN (214-363): 1.04e-26: 112: 11.92
+	Hs
		1288369 BAZ2A_HUMAN (149-547): 4.67e-72: 268: 15.57		SNR40_HUMAN (251-359): 3.31e-21: 95.1: 14.55
+	Sc
		767631 GCN5_YEAST (435-548): 5.76e-20: 96.4: 29.83		GLE2_YEAST (1-365): 2.25e-83: 259: 100.00
+	Hs
		1288368 BAZ2B_HUMAN (134-547): 2.87e-69: 259: 18.52		SNR40_HUMAN (251-359): 3.31e-21: 95.1: 14.55
+	Hs
		847053 SMCA4_HUMAN (199-590): 5.78e-62: 235: 11.04		SNR40_HUMAN (251-359): 3.31e-21: 95.1: 14.55
+	Sp
		252179 YK82_SCHPO (236-931): 2.16e-57: 214: 13.55		NLE1_SCHPO (237-363): 5.24e-24: 104: 10.85
+	Dm
		631309 BRM_DROME (199-648): 4.73e-58: 223: 10.35		EBI_DROME (254-361): 3.64e-16: 81.6: 11.57
+	Sp
		251276 YK82_SCHPO (236-931): 2.16e-57: 214: 13.55		TAF73_SCHPO (38-331): 1.04e-18: 89.4: 18.75
+	Hs
		903405 CBP_HUMAN (330-549): 7.1e-40: 164: 18.94		WDR5_HUMAN (2-67): 7.82e-10: 61.6: 10.29
+	Hs
		903409 KAT2B_HUMAN (429-544): 6.55e-37: 152: 26.72		WDR5_HUMAN (2-67): 7.82e-10: 61.6: 10.29
+	Hs
		903408 KAT2A_HUMAN (429-536): 2.27e-34: 144: 26.85		WDR5_HUMAN (2-67): 7.82e-10: 61.6: 10.29
+	Mm
		903679 KAT2A_MOUSE (429-536): 2.21e-34: 144: 26.85		WDR5_MOUSE (2-67): 7.82e-10: 61.6: 10.29
+	Dm
		1358857 Q9VTZ1_DROME (428-531): 1.53e-25: 116: 32.69		WDS_DROME (2-68): 6.34e-11: 65.1: 10.15
+	Hs
		1162755 ATAD2_HUMAN (429-725): 1.13e-15: 84.9: 22.46		SNR40_HUMAN (251-359): 3.31e-21: 95.1: 14.55
+	Hs
		600117 TAF1_HUMAN (337-877): 1.46e-21: 104: 13.62		WDR5_HUMAN (2-67): 7.82e-10: 61.6: 10.29