HitPredict

Interactor 1: RUXGL (A8MWD9)
Putative small nuclear ribonucleoprotein G-like protein 15
Gene: SNRPGP15

Interactor 2: SF3B1 (O75533)
Splicing factor 3B subunit 1 (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155)
Gene: SF3B1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005686 - U2 snRNP GO:0005689 - U12-type spliceosomal complex GO:0071004 - U2-type prespliceosome and 1 others more... GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 76 Hs			1 1304
+	Hs
		285855 RUXG_HUMAN (1-76): 5.36e-30: 102: 94.74		SF3B1_HUMAN (1-1304): 0: 1351: 100.00
+	Hs
		285866 RSMN_HUMAN (1-70): 9.36e-23: 88.6: 21.25		SF3B1_HUMAN (1-1304): 0: 1351: 100.00
+	Hs
		285854 RUXF_HUMAN (5-73): 9.09e-24: 87.1: 26.09		SF3B1_HUMAN (1-1304): 0: 1351: 100.00
+	Hs
		285793 RSMB_HUMAN (1-70): 5.03e-22: 86.7: 21.25		SF3B1_HUMAN (1-1304): 0: 1351: 100.00
+	Sc
		820820 RUXG_YEAST (7-76): 5.35e-22: 82.3: 50.69		SF3B1_YEAST (387-1304): 0: 927: 50.65
+	Sc
		892770 RUXF_YEAST (5-73): 2.83e-21: 80.6: 24.29		SF3B1_YEAST (387-1304): 0: 927: 50.65
+	Sc
		892771 LSM3_YEAST (4-72): 4.34e-10: 52.6: 28.57		SF3B1_YEAST (387-1304): 0: 927: 50.65
+	Hs
		319048 RSMB_HUMAN (1-70): 5.03e-22: 86.7: 21.25		K0754_HUMAN (2-340): 5.67e-23: 109: 12.64
+	At
		1182160 LSM1B_ARATH (1-74): 2.07e-24: 89.8: 32.53		2AAA_ARATH (955-1268): 5.47e-22: 104: 15.00