HitPredict

Interactor 1: MARCS (P29966)
Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (80K-L protein) (PKCSL)
Gene: MARCKS

Interactor 2: NOTC1 (P46531)
Neurogenic locus notch homolog protein 1 (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]
Gene: NOTCH1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0021915 - neural tube development
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 332 Hs			1 2555
+	Hs
		592949 TITIN_HUMAN (3-293): 7.73e-09: 59.5: 13.74		ANK1_HUMAN (1799-2553): 1.79e-115: 411: 14.27
+	Hs
		715564 MARCS_HUMAN (1-322): 1.8e-16: 81: 100.00		ANK3_HUMAN (1899-2550): 1.41e-96: 353: 15.78
+	Hs
		715544 MARCS_HUMAN (1-322): 1.8e-16: 81: 100.00		ANK2_HUMAN (1968-2550): 4.02e-91: 335: 13.91
+	Hs
		177277 TITIN_HUMAN (3-293): 7.73e-09: 59.5: 13.74		ANR28_HUMAN (1999-2495): 3.31e-58: 223: 14.37
+	Hs
		715552 MARCS_HUMAN (1-322): 1.8e-16: 81: 100.00		NOTC2_HUMAN (2-419): 1.94e-26: 121: 23.60
+	Dm
		119660 M9PB30_DROME (80-326): 8.97e-09: 59.1: 8.46		M9PB30_DROME (12-695): 1.2e-10: 69.9: 18.55