HitPredict

Interactor 1: 1433B (P35213)
14-3-3 protein beta/alpha (Prepronerve growth factor RNH-1) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: Ywhab

Interactor 2: KS6A1 (Q63531)
Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1)
Gene: Rps6ka1

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	12618428
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Rn			1 735
+	Hs
		683368 1433B_HUMAN (1-246): 6.02e-144: 404: 98.37		KS6A1_HUMAN (1-735): 0: 831: 97.55
+	Hs
		683216 1433B_HUMAN (1-246): 6.02e-144: 404: 98.37		KS6A3_HUMAN (1-734): 0: 788: 79.22
+	Dm
		955037 1433E_DROME (3-245): 7.18e-144: 404: 64.90		Q9VR61_DROME (8-729): 0: 711: 51.17
+	Hs
		270395 1433Z_HUMAN (3-244): 2.16e-141: 397: 86.78		KS6A5_HUMAN (47-730): 0: 702: 40.92
+	Hs
		272852 1433B_HUMAN (1-246): 6.02e-144: 404: 98.37		KS6A4_HUMAN (51-734): 0: 647: 41.59
+	Hs
		681770 1433E_HUMAN (3-243): 8.03e-144: 404: 65.02		AKT1_HUMAN (321-734): 1.22e-123: 379: 22.17
+	Hs
		681776 1433Z_HUMAN (3-244): 2.16e-141: 397: 86.78		AKT1_HUMAN (321-734): 1.22e-123: 379: 22.17
+	Hs
		568616 1433E_HUMAN (3-243): 8.03e-144: 404: 65.02		KAPCA_HUMAN (405-712): 1.55e-116: 356: 29.50
+	Hs
		647835 1433B_HUMAN (1-246): 6.02e-144: 404: 98.37		MARK3_HUMAN (373-695): 2.01e-110: 353: 25.76
+	Hs
		647862 1433E_HUMAN (3-243): 8.03e-144: 404: 65.02		MARK3_HUMAN (373-695): 2.01e-110: 353: 25.76
+	Xl
		223344 O57468_XENLA (4-243): 4.02e-143: 402: 65.29		Q804T2_XENLA (373-705): 8.43e-111: 354: 25.29
+	Mm
		910231 1433E_MOUSE (3-243): 8.03e-144: 404: 65.02		MARK3_MOUSE (373-695): 5.53e-110: 352: 25.46
+	Hs
		568620 1433Z_HUMAN (3-244): 2.16e-141: 397: 86.78		KAPCA_HUMAN (405-712): 1.55e-116: 356: 29.50
+	Mm
		926780 1433Z_MOUSE (3-244): 5.73e-142: 399: 86.36		MARK3_MOUSE (373-695): 5.53e-110: 352: 25.46
+	Hs
		647869 1433Z_HUMAN (3-244): 2.16e-141: 397: 86.78		MARK3_HUMAN (373-695): 2.01e-110: 353: 25.76
+	Mm
		926770 1433Z_MOUSE (3-244): 5.73e-142: 399: 86.36		KAPCB_MOUSE (417-712): 2.87e-112: 345: 30.42
+	Hs
		909590 1433E_HUMAN (3-243): 8.03e-144: 404: 65.02		KS6A2_HUMAN (4-321): 4.41e-100: 325: 23.64
+	At
		788319 14331_ARATH (2-240): 4.79e-143: 402: 62.55		KPK1_ARATH (416-696): 2.04e-96: 308: 29.25
+	Mm
		926837 1433Z_MOUSE (3-244): 5.73e-142: 399: 86.36		KS6A5_MOUSE (136-318): 1.11e-66: 238: 30.46
+	Hs
		116995 1433Z_HUMAN (3-244): 2.16e-141: 397: 86.78		SGK1_HUMAN (415-667): 6.23e-30: 125: 33.85