HitPredict

Interactor 1: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Interactor 2: HIF1A (Q16665)
Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein) (Basic-helix-loop-helix-PAS protein MOP1) (Class E basic helix-loop-helix protein 78) (bHLHe78) (Member of PAS protein 1) (PAS domain-containing protein 8)
Gene: HIF1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.60 0.732

The method score is based on:

Property Details
Experiments 24650032, 23246962, 22865883, 23671189, 17220880, 18593917
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000791 - euchromatin
GO:0001837 - epithelial to mesenchymal transition
GO:0002052 - positive regulation of neuroblast proliferation
GO:0002062 - chondrocyte differentiation
GO:0003151 - outflow tract morphogenesis
and 16 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 781
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024