HitPredict

Interactor 1: PDIA3 (P30101)
Protein disulfide-isomerase A3 (EC 5.3.4.1) (58 kDa glucose-regulated protein) (58 kDa microsomal protein) (p58) (Disulfide isomerase ER-60) (Endoplasmic reticulum resident protein 57) (ER protein 57) (ERp57) (Endoplasmic reticulum resident protein 60) (ER protein 60) (ERp60)
Gene: PDIA3

Interactor 2: TERA (P55072)
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP)
Gene: VCP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	29540532, 35562734, 37776851
Identification Methods	proximity labelling technology, affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005783 - endoplasmic reticulum GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 505 Hs			1 806
+	Hs
		452212 PDIA1_HUMAN (3-482): 3.49e-117: 356: 33.06		TERA_HUMAN (1-806): 0: 774: 100.00
+	Dm
		1191648 Q3YMU0_DROME (1-500): 4.38e-116: 352: 44.64		TERA_DROME (5-806): 0: 760: 83.09
+	Dm
		929492 PDI_DROME (1-488): 9.9e-108: 331: 31.72		TERA_DROME (5-806): 0: 760: 83.09
+	Sc
		610102 PDI_YEAST (13-483): 2.91e-87: 279: 27.55		CDC48_YEAST (2-806): 0: 740: 67.75
+	Hs
		934836 DJC10_HUMAN (11-244): 2.95e-32: 133: 16.67		TERA_HUMAN (1-806): 0: 774: 100.00
+	Hs
		935067 ERP44_HUMAN (368-496): 2.96e-25: 109: 21.64		TERA_HUMAN (1-806): 0: 774: 100.00
+	Hs
		566602 PDIA4_HUMAN (376-494): 1.94e-23: 106: 34.71		TERA_HUMAN (1-806): 0: 774: 100.00
+	Dm
		1267921 PDIA6_DROME (367-472): 1.2e-23: 105: 34.91		TERA_DROME (5-806): 0: 760: 83.09
+	Hs
		934639 PDIA6_HUMAN (385-471): 3.14e-10: 64.3: 40.91		TERA_HUMAN (1-806): 0: 774: 100.00