HitPredict

Interactor 1: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Interactor 2: KAT6A (Q92794)
Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger protein) (Runt-related transcription factor-binding protein 2) (Zinc finger protein 220)
Gene: KAT6A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.625

Property	Details
Experiments	27775714, 11742995
Identification Methods	pull down, x-ray crystallography, enzymatic study
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000786 - nucleosome GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 2004
+	Hs
		309689 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		KAT7_HUMAN (166-780): 5.67e-142: 457: 33.76
+	Hs
		935245 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		KAT8_HUMAN (357-789): 2.81e-138: 441: 37.73
+	Hs
		935077 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		KAT5_HUMAN (292-779): 3.96e-132: 426: 34.82
+	Hs
		934705 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CHD3_HUMAN (37-504): 1.12e-72: 273: 14.40
+	Hs
		935016 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CHD5_HUMAN (165-468): 3.23e-53: 209: 12.87
+	Hs
		1086233 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CHD5_HUMAN (165-468): 3.23e-53: 209: 12.87
+	Hs
		934770 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CHD4_HUMAN (63-504): 3.51e-50: 199: 11.13
+	Hs
		1059646 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CHD4_HUMAN (63-504): 3.51e-50: 199: 11.13
+	Hs
		935065 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		REQU_HUMAN (39-326): 5.71e-54: 196: 27.24
+	At
		886465 H33_ARATH (1-136): 7.67e-62: 187: 96.32		ATXR5_ARATH (263-614): 3.3e-53: 194: 16.44
+	Hs
		935064 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		DPF3_HUMAN (95-310): 5.14e-50: 184: 30.32
+	At
		886470 H33_ARATH (1-136): 7.67e-62: 187: 96.32		ATXR6_ARATH (235-614): 6.3e-50: 183: 13.81
+	Hs
		935047 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		KAT6B_HUMAN (924-2004): 4.93e-40: 166: 37.06
+	Hs
		935025 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		PHF10_HUMAN (183-318): 2.33e-41: 162: 43.36
+	Hs
		934763 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		MDC1_HUMAN (807-1825): 3.66e-30: 133: 11.19
+	Hs
		152625 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		KMT2D_HUMAN (193-311): 2.94e-25: 117: 33.61
+	Hs
		935004 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		KMT2C_HUMAN (229-311): 4.1e-22: 107: 37.35
+	Hs
		1086228 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		KMT2C_HUMAN (229-311): 4.1e-22: 107: 37.35
+	Hs
		934668 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		ANK2_HUMAN (749-1909): 1.85e-16: 88.5: 10.39
+	Hs
		935150 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		MINT_HUMAN (748-1864): 3.86e-13: 77.8: 10.17