HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: RING1 (Q06587)
E3 ubiquitin-protein ligase RING1 (EC 2.3.2.27) (Polycomb complex protein RING1) (RING finger protein 1) (RING-type E3 ubiquitin transferase RING1) (Really interesting new gene 1 protein)
Gene: RING1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.991

The method score is based on:

Property Details
Experiments 25416956, 24457600, 27705803, 29402932, 9199346, 32296183, 33961781, 16359901, 34316702, 19636380, 16751658, 22325352, 19451220, 22897849, 9858531, 24981860, 34133714, 35271311, 15386022, 22493164 and 2 others

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Identification Methods two hybrid, affinity chromatography technology, biochemical, pull down, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti bait coimmunoprecipitation, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RAWUL~RAWUL, zf-C3HC4_2~zf-C3HC4_2
Common GO terms GO:0000151 - ubiquitin ligase complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006338 - chromatin remodeling
and 3 others

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Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 326
Hs

1 406
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Last updated: 15 Jul 2024