HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: TR150 (Q9Y2W1)
Thyroid hormone receptor-associated protein 3 (BCLAF1 and THRAP3 family member 2) (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150)
Gene: THRAP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	24457600, 34316702
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 955
+	Hs
		718251 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		BCLF1_HUMAN (38-949): 3.55e-78: 276: 33.19
+	Hs
		1304196 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		TR150_HUMAN (1-955): 9.81e-127: 408: 100.00
+	Hs
		718326 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		718055 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		TITIN_HUMAN (105-799): 3.29e-11: 70: 7.20
+	Hs
		717965 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		MICA3_HUMAN (169-857): 2.66e-09: 63.4: 7.24
+	Hs
		1304146 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		BCLF1_HUMAN (38-949): 3.55e-78: 276: 33.19
+	Hs
		1019387 TRI26_HUMAN (5-210): 1e-49: 175: 16.59		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		1056961 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		MDC1_HUMAN (2-649): 1.14e-11: 71.2: 8.49
+	Hs
		1264788 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		TITIN_HUMAN (105-799): 3.29e-11: 70: 7.20
+	Hs
		282654 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		MDC1_HUMAN (2-649): 1.14e-11: 71.2: 8.49