HitPredict

Interactor 1: PCGF2 (P35227)
Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144)
Gene: PCGF2

Interactor 2: SCMH1 (Q96GD3)
Polycomb protein SCMH1 (Sex comb on midleg homolog 1)
Gene: SCMH1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	28514442, 24981860, 33961781, 22325352
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 344 Hs			1 660
+	Hs
		718098 BMI1_HUMAN (1-341): 3.88e-98: 295: 61.40		SCMH1_HUMAN (1-660): 0: 785: 100.00
+	Hs
		718408 PCGF2_HUMAN (1-344): 8.96e-118: 345: 100.00		PHC2_HUMAN (209-658): 2.19e-86: 290: 18.09
+	Mm
		620794 PCGF2_MOUSE (1-342): 3.16e-110: 326: 95.91		PHC2_MOUSE (209-658): 1.15e-85: 288: 17.61
+	Hs
		1220909 R4GMX3_HUMAN (1-341): 1.22e-101: 308: 61.40		PHC2_HUMAN (209-658): 2.19e-86: 290: 18.09
+	Hs
		717999 BMI1_HUMAN (1-341): 3.88e-98: 295: 61.40		PHC2_HUMAN (209-658): 2.19e-86: 290: 18.09
+	Hs
		718412 PCGF2_HUMAN (1-344): 8.96e-118: 345: 100.00		PHC3_HUMAN (231-658): 6.64e-66: 235: 20.73
+	Mm
		639480 BMI1_MOUSE (1-341): 4.26e-96: 290: 61.11		PHC2_MOUSE (209-658): 1.15e-85: 288: 17.61
+	Mm
		620790 PCGF2_MOUSE (1-342): 3.16e-110: 326: 95.91		PHC3_MOUSE (231-658): 9.6e-67: 238: 20.09
+	Hs
		718390 PCGF2_HUMAN (1-344): 8.96e-118: 345: 100.00		PHC1_HUMAN (296-657): 2.38e-59: 217: 19.06
+	Mm
		620786 PCGF2_MOUSE (1-342): 3.16e-110: 326: 95.91		PHC1_MOUSE (234-657): 5.58e-59: 216: 17.30
+	Dr
		1225025 BMI1A_DANRE (1-340): 1.28e-94: 286: 61.77		PHC2_DANRE (231-658): 3.02e-73: 254: 17.90
+	Hs
		718416 PCGF2_HUMAN (1-344): 8.96e-118: 345: 100.00		LMBL2_HUMAN (1-315): 5.74e-50: 187: 19.32
+	Hs
		718028 BMI1_HUMAN (1-341): 3.88e-98: 295: 61.40		PHC3_HUMAN (231-658): 6.64e-66: 235: 20.73
+	Mm
		639476 BMI1_MOUSE (1-341): 4.26e-96: 290: 61.11		PHC3_MOUSE (231-658): 9.6e-67: 238: 20.09
+	Hs
		717684 BMI1_HUMAN (1-341): 3.88e-98: 295: 61.40		PHC1_HUMAN (296-657): 2.38e-59: 217: 19.06
+	Mm
		639473 BMI1_MOUSE (1-341): 4.26e-96: 290: 61.11		PHC1_MOUSE (234-657): 5.58e-59: 216: 17.30
+	Hs
		718083 BMI1_HUMAN (1-341): 3.88e-98: 295: 61.40		LMBL2_HUMAN (1-315): 5.74e-50: 187: 19.32
+	Hs
		718440 PCGF2_HUMAN (1-344): 8.96e-118: 345: 100.00		SCML1_HUMAN (477-659): 5.31e-27: 114: 33.00
+	Hs
		718311 BMI1_HUMAN (1-341): 3.88e-98: 295: 61.40		SCML1_HUMAN (477-659): 5.31e-27: 114: 33.00
+	Hs
		718330 BMI1_HUMAN (1-341): 3.88e-98: 295: 61.40		SCML2_HUMAN (1-126): 2.16e-23: 107: 26.00