Interactor 1: SPB6 (P35237)
Serpin B6 (Cytoplasmic antiproteinase) (CAP) (Peptidase inhibitor 6) (PI-6) (Placental thrombin inhibitor)
Gene: SERPINB6

Interactor 2: SPB8 (P50452)
Serpin B8 (Cytoplasmic antiproteinase 2) (CAP-2) (CAP2) (Peptidase inhibitor 8) (PI-8)
Gene: SERPINB8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Serpin~Serpin
Common GO terms GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005615 - extracellular space
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0010951 - negative regulation of endopeptidase activity
and 2 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 376
Hs

1 374
+ Hs
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Last updated: 15 Jul 2024