HitPredict

Interactor 1: SC6A1 (P30531)
Sodium- and chloride-dependent GABA transporter 1 (GAT-1) (Solute carrier family 6 member 1)
Gene: SLC6A1

Interactor 2: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	39079530
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007268 - chemical synaptic transmission GO:0016020 - membrane GO:0030424 - axon GO:0043025 - neuronal cell body and 1 others more... GO:0050808 - synapse organization
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 599 Hs			1 140
+	Mm
		727619 SC6A1_MOUSE (1-599): 0: 776: 98.00		SYUB_MOUSE (1-126): 1.53e-33: 116: 58.02
+	Hs
		727552 SC6A4_HUMAN (3-580): 0: 663: 42.20		SYUA_HUMAN (1-140): 1e-57: 177: 100.00
+	Hs
		791304 SC6A3_HUMAN (2-583): 0: 654: 43.41		SYUA_HUMAN (1-140): 1e-57: 177: 100.00
+	Rn
		663642 SC6A3_RAT (2-583): 0: 651: 42.98		SYUA_RAT (1-140): 4.93e-58: 178: 95.00
+	Mm
		237097 SC6A3_MOUSE (2-583): 0: 651: 43.15		SYUA_MOUSE (1-140): 8.9e-58: 177: 95.00
+	Hs
		663627 SC6A2_HUMAN (34-576): 0: 645: 46.21		SYUA_HUMAN (1-140): 1e-57: 177: 100.00
+	Hs
		791660 SC6A7_HUMAN (44-577): 0: 616: 45.77		SYUA_HUMAN (1-140): 1e-57: 177: 100.00
+	Hs
		302694 SC6A4_HUMAN (3-580): 0: 663: 42.20		SYUG_HUMAN (1-100): 1.67e-28: 102: 66.00
+	Hs
		791747 S6A20_HUMAN (41-560): 1.03e-170: 499: 33.62		SYUA_HUMAN (1-140): 1e-57: 177: 100.00
+	Hs
		791719 S6A15_HUMAN (19-555): 1.02e-147: 445: 25.37		SYUA_HUMAN (1-140): 1e-57: 177: 100.00