HitPredict

Interactor 1: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Interactor 2: SC6A7 (Q99884)
Sodium-dependent proline transporter (Solute carrier family 6 member 7)
Gene: SLC6A7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	39079530
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 636
+	Rn
		663642 SYUA_RAT (1-140): 4.93e-58: 178: 95.00		SC6A3_RAT (33-578): 0: 683: 47.07
+	Hs
		791304 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		SC6A3_HUMAN (16-578): 0: 683: 45.29
+	Mm
		237097 SYUA_MOUSE (1-140): 8.9e-58: 177: 95.00		SC6A3_MOUSE (33-578): 0: 682: 46.89
+	Hs
		663627 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		SC6A2_HUMAN (34-578): 0: 671: 46.15
+	Hs
		720381 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		SC6A1_HUMAN (3-578): 0: 664: 43.97
+	Hs
		727552 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		SC6A4_HUMAN (27-577): 0: 643: 43.94
+	Mm
		727619 SYUB_MOUSE (1-126): 1.53e-33: 116: 58.02		SC6A1_MOUSE (3-578): 0: 665: 44.31
+	Hs
		302694 SYUG_HUMAN (1-100): 1.67e-28: 102: 66.00		SC6A4_HUMAN (27-577): 0: 643: 43.94
+	Hs
		791747 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		S6A20_HUMAN (37-560): 1.3e-178: 521: 33.28
+	Hs
		791719 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		S6A15_HUMAN (342-603): 9.08e-62: 220: 30.94