Interactor 1: IRS1 (P35569)
Insulin receptor substrate 1 (IRS-1)
Gene: IRS1
Interactor 2: KS6B1 (Q8BSK8)
Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (S6K) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)
Gene: Rps6kb1
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15249583 |
| Identification Methods | enzymatic study |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PH~Pkinase |
| Common GO terms | GO:0005737 - cytoplasm GO:0016477 - cell migration GO:0032869 - cellular response to insulin stimulus GO:0046627 - negative regulation of insulin receptor signaling pathway |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
