HitPredict

Interactor 1: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Interactor 2: RBM14 (Q96PK6)
RNA-binding protein 14 (Paraspeckle protein 2) (PSP2) (RNA-binding motif protein 14) (RRM-containing coactivator activator/modulator) (Synaptotagmin-interacting protein) (SYT-interacting protein)
Gene: RBM14

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29884807
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 526 Hs			1 669
+	Mm
		1207135 Q8BQ46_MOUSE (42-460): 2.55e-40: 155: 48.34		RBM4_MOUSE (1-365): 1.5e-62: 214: 27.40
+	Hs
		516620 RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10		PABP1_HUMAN (3-538): 5.24e-33: 137: 13.49
+	Hs
		516383 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		PABP1_HUMAN (3-538): 5.24e-33: 137: 13.49
+	Hs
		516744 PPIE_HUMAN (280-514): 1.23e-31: 125: 19.46		PABP1_HUMAN (3-538): 5.24e-33: 137: 13.49
+	Hs
		516768 RBM8A_HUMAN (219-366): 3.35e-27: 109: 26.35		PABP1_HUMAN (3-538): 5.24e-33: 137: 13.49
+	Hs
		1031411 RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10		PABP4_HUMAN (71-151): 5.98e-10: 64.2: 23.60
+	At
		955331 CYP59_ARATH (205-524): 5.51e-32: 130: 13.45		RS40_ARATH (3-316): 1.62e-19: 92.7: 24.23
+	Hs
		726795 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		PABP4_HUMAN (71-151): 5.98e-10: 64.2: 23.60
+	Hs
		474021 PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00		PAB4L_HUMAN (3-160): 1.38e-35: 140: 21.71
+	At
		955324 CYP59_ARATH (205-524): 5.51e-32: 130: 13.45		SRS31_ARATH (3-216): 1.17e-16: 82.3: 22.18
+	Hs
		642763 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		ELAV4_HUMAN (4-154): 5.18e-16: 82.3: 24.56
+	Hs
		516495 PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00		PABP1_HUMAN (3-538): 5.24e-33: 137: 13.49
+	Hs
		1020353 PPIE_HUMAN (280-514): 1.23e-31: 125: 19.46		ELAV2_HUMAN (4-154): 1.38e-16: 83.8: 25.15
+	Hs
		516339 PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44		PABP1_HUMAN (3-538): 5.24e-33: 137: 13.49
+	Hs
		1031507 RBM8A_HUMAN (219-366): 3.35e-27: 109: 26.35		PABP4_HUMAN (71-151): 5.98e-10: 64.2: 23.60
+	Hs
		1119141 PAP1L_HUMAN (182-382): 2.39e-13: 74.7: 13.43		PABP5_HUMAN (3-169): 2.16e-17: 86.5: 26.53
+	Hs
		516635 PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44		PABP5_HUMAN (3-169): 2.16e-17: 86.5: 26.53
+	Hs
		1020249 PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00		ELAV2_HUMAN (4-154): 1.38e-16: 83.8: 25.15
+	Hs
		516484 PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44		ELAV2_HUMAN (4-154): 1.38e-16: 83.8: 25.15