Protein: CLPB
Chaperone protein ClpB (ClpB disaggregase) (Heat shock protein F84.1)

Gene: CLPB
Organism: Escherichia coli K-12
Interactions: 90
UniProt ID: P63284

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0009408 - response to heat
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

993869

CLPB
Chaperone protein ClpB

3

11

Small-scale

0.854

High

495731

CLPS
ATP-dependent Clp protease adapter protein ClpS

2

3

Small-scale

0.776

High

501042

SSPB
Stringent starvation protein B

1

1

High-throughput

0.691

High

491240

DNAK
Chaperone protein DnaK

3

9

Small-scale

0.672

High

490316

CLPX
ATP-dependent Clp protease ATP-binding subunit ClpX

1

11

High-throughput

0.625

High

494727

RUVB
Holliday junction branch migration complex subunit RuvB

2

9

High-throughput

0.601

High

495671

SYK2
Lysine--tRNA ligase, heat inducible

2

3

High-throughput

0.588

High

506298

EFTU1
Elongation factor Tu 1

2

7

High-throughput

0.588

High

722834

EVGS
Sensor protein EvgS

2

3

High-throughput

0.588

High

788379

RLMN
Dual-specificity RNA methyltransferase RlmN

2

1

High-throughput

0.588

High

501433

SUBI
Sulfate-binding protein

2

0

High-throughput

0.585

High

368835

SYA
Alanine--tRNA ligase

1

2

High-throughput

0.536

High

480558

GRPE
Protein GrpE

1

1

High-throughput

0.536

High

483730

PUTA
Bifunctional protein PutA [Includes: Proline dehydrogenase

1

5

High-throughput

0.536

High

495859

RPOC
DNA-directed RNA polymerase subunit beta'

1

9

High-throughput

0.536

High

498818

SDHA
Succinate dehydrogenase flavoprotein subunit

1

5

High-throughput

0.536

High

540790

YIBD
Uncharacterized glycosyltransferase YibD

1

1

High-throughput

0.536

High

616967

NADE
NH(3)-dependent NAD(+) synthetase

1

1

High-throughput

0.536

High

790751

ZNTA
Zinc/cadmium/lead-transporting P-type ATPase

1

3

High-throughput

0.536

High

950953

RL2
Large ribosomal subunit protein uL2

1

4

High-throughput

0.536

High

993874

PBPC
Penicillin-binding protein 1C

1

1

High-throughput

0.536

High

449939

DUT
Deoxyuridine 5'-triphosphate nucleotidohydrolase

1

0

High-throughput

0.513

High

500886

PHOB
Phosphate regulon transcriptional regulatory protein PhoB

1

0

High-throughput

0.513

High

501485

RPOH
RNA polymerase sigma factor RpoH

1

0

High-throughput

0.513

High

659731

GLXK1
Glycerate 2-kinase

1

0

High-throughput

0.513

High

664163

LPXM
Lipid A biosynthesis myristoyltransferase

1

0

High-throughput

0.513

High

680659

WAAP
Lipopolysaccharide core heptose(I) kinase WaaP

1

0

High-throughput

0.513

High

690641

WAAY
Lipopolysaccharide core heptose(II) kinase WaaY

1

0

High-throughput

0.513

High

788845

FXSA
UPF0716 protein FxsA

1

0

High-throughput

0.513

High

789055

PT1P
Phosphoenolpyruvate-dependent phosphotransferase system

1

0

High-throughput

0.513

High

811778

ULAF
L-ribulose-5-phosphate 4-epimerase UlaF

1

0

High-throughput

0.513

High

811796

INTB
Putative protein IntB

1

0

High-throughput

0.513

High

993879

QUEF
NADPH-dependent 7-cyano-7-deazaguanine reductase

1

0

High-throughput

0.513

High

494821

SUCC
Succinate--CoA ligase [ADP-forming] subunit beta

1

2

High-throughput

0.500

High

498017

YBDG
Mechanosensing system component YbdG

1

1

High-throughput

0.489

High

664113

MANB
Phosphomannomutase

1

1

High-throughput

0.489

High

382747

RS7
Small ribosomal subunit protein uS7

1

4

High-throughput

0.484

High

489922

CH60
Chaperonin GroEL

1

3

High-throughput

0.484

High

493051

RL29
Large ribosomal subunit protein uL29

1

1

High-throughput

0.484

High

493284

RS10
Small ribosomal subunit protein uS10

1

5

High-throughput

0.484

High

493822

RS2
Small ribosomal subunit protein uS2

1

7

High-throughput

0.484

High

494390

RS8
Small ribosomal subunit protein uS8

1

3

High-throughput

0.484

High

497363

MREB
Cell shape-determining protein MreB

1

17

High-throughput

0.484

High

497535

RL13
Large ribosomal subunit protein uL13

1

5

High-throughput

0.484

High

501255

RL21
Large ribosomal subunit protein bL21

1

1

High-throughput

0.484

High

501350

RS14
Small ribosomal subunit protein uS14

1

1

High-throughput

0.484

High

501721

IBPA
Small heat shock protein IbpA

1

1

High-throughput

0.484

High

785881

CBPA
Curved DNA-binding protein

1

3

High-throughput

0.484

High

951029

RL3
Large ribosomal subunit protein uL3

1

5

High-throughput

0.484

High

958605

RL22
Large ribosomal subunit protein uL22

1

5

High-throughput

0.484

High

993876

YDEP
Protein YdeP

1

1

High-throughput

0.484

High

498657

EXBB
Biopolymer transport protein ExbB

1

0

High-throughput

0.479

High

490188

CH10
Co-chaperonin GroES

1

3

High-throughput

0.479

High

491872

NAGB
Glucosamine-6-phosphate deaminase

1

1

High-throughput

0.479

High

598494

SYP
Proline--tRNA ligase

1

4

Small-scale

0.479

High

490487

HSCB
Co-chaperone protein HscB

1

0

High-throughput

0.464

High

499652

KBP
Potassium binding protein Kbp

1

0

High-throughput

0.464

High

501588

SAPC
Putrescine export system permease protein SapC

1

0

High-throughput

0.464

High

717678

THIG
Thiazole synthase

1

0

High-throughput

0.464

High

788405

LAST
Uncharacterized tRNA/rRNA methyltransferase LasT

1

0

High-throughput

0.464

High

790481

MASZ
Malate synthase G

1

0

High-throughput

0.464

High

993871

PTSN
Nitrogen regulatory protein

1

0

High-throughput

0.464

High

496109

OMPA
Outer membrane protein A

1

0

High-throughput

0.458

High

496170

RIMI
[Ribosomal protein bS18]-alanine N-acetyltransferase

1

0

High-throughput

0.458

High

500273

RIMO
Ribosomal protein uS12 methylthiotransferase RimO

1

0

High-throughput

0.458

High

500992

RMF
Ribosome modulation factor

1

0

High-throughput

0.458

High

664147

HYPD
Hydrogenase maturation factor HypD

1

0

High-throughput

0.458

High

724365

POTF
Putrescine-binding periplasmic protein PotF

1

0

High-throughput

0.458

High

861477

TORZ
Trimethylamine-N-oxide reductase 2

1

1

High-throughput

0.457

High

473321

DNAJ
Chaperone protein DnaJ

1

7

Small-scale

0.445

High

498873

G6PD
Glucose-6-phosphate 1-dehydrogenase

1

1

Small-scale

0.445

High

495879

RBN
Ribonuclease BN

1

2

High-throughput

0.442

High

393908

PBPA
Penicillin-binding protein 1A

1

1

High-throughput

0.437

High

744424

YJBH
Uncharacterized lipoprotein YjbH

2

0

High-throughput

0.318

High

749427

TSUB
Putative sulfur carrier protein TsuB

1

0

High-throughput

0.304

High

993870

YNFC
UPF0257 lipoprotein YnfC

1

0

High-throughput

0.282

High

365991

BGAL
Beta-galactosidase

1

0

High-throughput

0.279

Low

501506

SMP
Probable inner membrane protein Smp

1

0

High-throughput

0.279

Low

852423

YFAL
Probable autotransporter YfaL [Cleaved into: Probable secreted autotransporter protein YfaL; Probable autotransporter YfaL translocator]

1

0

High-throughput

0.279

Low

993873

YDDH
Uncharacterized protein YddH

1

0

High-throughput

0.279

Low

993875

YKGF
Uncharacterized electron transport protein YkgF

1

0

High-throughput

0.279

Low

993878

ALLA
Ureidoglycolate lyase

1

0

High-throughput

0.279

Low

993880

UIDC
Membrane-associated protein UidC

1

0

High-throughput

0.279

Low

498484

CCMB
Heme exporter protein B

1

0

High-throughput

0.253

Low

852439

YHFT
Uncharacterized protein YhfT

1

0

High-throughput

0.253

Low

993872

GFCB
Uncharacterized lipoprotein GfcB

1

0

High-throughput

0.253

Low

993877

ECPD
Fimbria adhesin EcpD

1

0

High-throughput

0.253

Low

790833

WBBK
Putative glycosyltransferase WbbK

1

0

High-throughput

0.249

Low

852442

DXR
1-deoxy-D-xylulose 5-phosphate reductoisomerase

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025