HitPredict

Interactor 1: MPE1 (P35728)
Protein MPE1
Gene: MPE1

Interactor 2: CFT2 (Q12102)
Cleavage factor two protein 2 (105 kDa protein associated with polyadenylation factor I)
Gene: CFT2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.749

Property	Details
Experiments	11713271, 11805826, 16429126, 12819204, 16554755, 30737185, 37968396, 14759368
Identification Methods	tandem affinity purification, affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005847 - mRNA cleavage and polyadenylation specificity factor complex GO:0030846 - termination of RNA polymerase II transcription, poly(A)-coupled
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 441 Sc			1 859
+	Hs
		1191735 RBBP6_HUMAN (3-439): 1.23e-115: 373: 27.16		CPSF2_HUMAN (14-859): 0: 765: 19.40
+	Sc
		728168 MPE1_YEAST (1-441): 0: 564: 100.00		YSH1_YEAST (2-430): 2.45e-134: 421: 15.86
+	Hs
		1191742 RBBP6_HUMAN (3-439): 1.23e-115: 373: 27.16		CPSF3_HUMAN (10-468): 6.1e-151: 461: 16.99