HitPredict

Interactor 1: K22E (P35908)
Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (CK-2e) (Epithelial keratin-2e) (Keratin-2 epidermis) (Keratin-2e) (K2e) (Type-II keratin Kb2)
Gene: KRT2

Interactor 2: K1C24 (Q2M2I5)
Keratin, type I cytoskeletal 24 (Cytokeratin-24) (CK-24) (Keratin-24) (K24) (Type I keratin-24)
Gene: KRT24

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	36949045
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Filament~Filament
Common GO terms	GO:0005829 - cytosol GO:0005882 - intermediate filament GO:0045109 - intermediate filament organization GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 639 Hs			1 525
+	Hs
		409094 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		K1C24_HUMAN (1-525): 5.38e-165: 479: 100.00
+	Hs
		409134 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		K1C28_HUMAN (27-525): 1.47e-154: 451: 52.29
+	Hs
		409137 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		K1C25_HUMAN (68-523): 4.76e-149: 436: 52.94
+	Hs
		409054 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		K1C17_HUMAN (133-517): 4.06e-147: 430: 55.33
+	Hs
		408990 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		K1C13_HUMAN (129-468): 1.16e-145: 427: 59.71
+	Hs
		49549 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		A1A4E9_HUMAN (129-468): 1.55e-145: 427: 59.41
+	Hs
		444534 K2C7_HUMAN (86-542): 4.82e-131: 395: 52.62		K1C17_HUMAN (133-517): 4.06e-147: 430: 55.33
+	Hs
		409000 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		K1C15_HUMAN (140-452): 1.9e-119: 360: 60.06
+	Hs
		359290 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		K1C14_HUMAN (104-515): 3.58e-118: 358: 51.70
+	Hs
		408980 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		K1C19_HUMAN (134-452): 2.1e-119: 358: 58.62
+	Hs
		409135 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		K1C27_HUMAN (62-525): 1.2e-116: 354: 54.62
+	Hs
		409136 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		K1C26_HUMAN (67-525): 1.1e-115: 351: 51.29
+	Hs
		380548 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		K1C10_HUMAN (135-450): 1.02e-141: 422: 68.35
+	Hs
		409082 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		K1H1_HUMAN (134-452): 2.14e-99: 308: 48.59
+	Hs
		359288 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		K1C14_HUMAN (104-515): 3.58e-118: 358: 51.70
+	Hs
		380538 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		K1C19_HUMAN (134-452): 2.1e-119: 358: 58.62
+	Hs
		409184 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		KRT35_HUMAN (46-456): 9.07e-76: 248: 43.34
+	Hs
		280770 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		KRT36_HUMAN (46-521): 1.01e-74: 245: 41.39
+	Hs
		409072 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		K1H2_HUMAN (51-456): 1.77e-73: 242: 39.81
+	Hs
		280768 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		KRT36_HUMAN (46-521): 1.01e-74: 245: 41.39