HitPredict

Interactor 1: VGFR3 (P35916)
Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)
Gene: FLT4

Interactor 2: SAR1B (Q9Y6B6)
Small COPII coat GTPase SAR1B (EC 3.6.5.2) (GTP-binding protein B) (GTBPB) (Secretion-associated Ras-related GTPase 1B)
Gene: SAR1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1363 Hs			1 198
+	Hs
		574612 VGFR3_HUMAN (1-1363): 0: 982: 100.00		ARF4_HUMAN (10-197): 2.61e-74: 223: 27.66
+	Hs
		729257 VGFR3_HUMAN (1-1363): 0: 982: 100.00		ARF6_HUMAN (21-196): 3.66e-74: 222: 30.11
+	Hs
		729366 VGFR3_HUMAN (1-1363): 0: 982: 100.00		SAR1A_HUMAN (1-198): 8.78e-63: 194: 89.90
+	Hs
		572582 VGFR1_HUMAN (19-1342): 0: 828: 38.63		ARF4_HUMAN (10-197): 2.61e-74: 223: 27.66
+	Hs
		572614 VGFR1_HUMAN (19-1342): 0: 828: 38.63		ARF6_HUMAN (21-196): 3.66e-74: 222: 30.11
+	Hs
		572686 VGFR1_HUMAN (19-1342): 0: 828: 38.63		SAR1A_HUMAN (1-198): 8.78e-63: 194: 89.90
+	Hs
		665572 EPHB2_HUMAN (372-1320): 3.34e-154: 495: 12.87		ARF6_HUMAN (21-196): 3.66e-74: 222: 30.11
+	Hs
		912916 EPHA7_HUMAN (392-1212): 1.3e-153: 492: 14.29		ARF6_HUMAN (21-196): 3.66e-74: 222: 30.11
+	Hs
		452347 PGFRB_HUMAN (19-555): 1.14e-123: 413: 22.80		ARF4_HUMAN (10-197): 2.61e-74: 223: 27.66
+	Hs
		574613 FLT3_HUMAN (837-1217): 1.41e-97: 338: 45.98		ARF4_HUMAN (10-197): 2.61e-74: 223: 27.66
+	Hs
		738190 FLT3_HUMAN (837-1217): 1.41e-97: 338: 45.98		ARF6_HUMAN (21-196): 3.66e-74: 222: 30.11
+	Hs
		738304 FLT3_HUMAN (837-1217): 1.41e-97: 338: 45.98		SAR1B_HUMAN (1-198): 3.26e-59: 185: 100.00
+	Hs
		574596 FGFR3_HUMAN (310-670): 4.9e-27: 121: 13.53		ARF4_HUMAN (10-197): 2.61e-74: 223: 27.66
+	Hs
		609559 FGFR3_HUMAN (310-670): 4.9e-27: 121: 13.53		SAR1A_HUMAN (1-198): 8.78e-63: 194: 89.90
+	Hs
		574595 FGFR4_HUMAN (535-810): 1.64e-14: 80.8: 15.79		ARF4_HUMAN (10-197): 2.61e-74: 223: 27.66
+	Hs
		507840 FGFR1_HUMAN (2-160): 6.17e-14: 78.9: 11.93		ARF4_HUMAN (10-197): 2.61e-74: 223: 27.66
+	Hs
		601491 FGFR2_HUMAN (2-160): 1e-11: 71.9: 14.12		ARF6_HUMAN (21-196): 3.66e-74: 222: 30.11
+	Hs
		507936 FGFR1_HUMAN (2-160): 6.17e-14: 78.9: 11.93		RAB1A_HUMAN (18-197): 7.2e-62: 192: 19.46