HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: NFAC2 (Q13469)
Nuclear factor of activated T-cells, cytoplasmic 2 (NF-ATc2) (NFATc2) (NFAT pre-existing subunit) (NF-ATp) (T-cell transcription factor NFAT1)
Gene: NFATC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27637333
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 246 Hs			1 925
+	Hs
		971487 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		NFAC2_HUMAN (1-925): 0: 860: 100.00
+	Hs
		990186 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		NFAC2_HUMAN (1-925): 0: 860: 100.00
+	Hs
		690978 1433T_HUMAN (3-244): 3.25e-127: 361: 81.82		NFAC2_HUMAN (1-925): 0: 860: 100.00
+	Hs
		966277 1433G_HUMAN (3-246): 1.92e-109: 317: 75.40		NFAC2_HUMAN (1-925): 0: 860: 100.00
+	Hs
		729789 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		NFAC3_HUMAN (25-921): 0: 707: 32.85
+	Hs
		990162 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		NFAC3_HUMAN (25-921): 0: 707: 32.85
+	Hs
		690957 1433T_HUMAN (3-244): 3.25e-127: 361: 81.82		NFAC3_HUMAN (25-921): 0: 707: 32.85
+	Hs
		340865 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		NFAC1_HUMAN (15-923): 0: 630: 41.20
+	Hs
		966255 1433G_HUMAN (3-246): 1.92e-109: 317: 75.40		NFAC3_HUMAN (25-921): 0: 707: 32.85
+	Hs
		1049243 1433F_HUMAN (4-244): 2.72e-107: 311: 75.51		NFAC3_HUMAN (25-921): 0: 707: 32.85
+	Hs
		730552 1433S_HUMAN (3-239): 3.4e-100: 293: 68.62		NFAC3_HUMAN (25-921): 0: 707: 32.85
+	Hs
		340828 1433T_HUMAN (3-244): 3.25e-127: 361: 81.82		NFAC1_HUMAN (15-923): 0: 630: 41.20
+	Hs
		990231 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		NFAC4_HUMAN (26-919): 0: 574: 33.78
+	Hs
		691012 1433T_HUMAN (3-244): 3.25e-127: 361: 81.82		NFAC4_HUMAN (26-919): 0: 574: 33.78
+	Hs
		626084 1433T_HUMAN (3-244): 3.25e-127: 361: 81.82		NFKB1_HUMAN (382-697): 2.52e-105: 351: 17.58
+	Hs
		319058 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		K0754_HUMAN (703-921): 8.11e-12: 71.9: 12.50
+	Hs
		319052 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		K0754_HUMAN (703-921): 8.11e-12: 71.9: 12.50
+	Hs
		319061 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		K0754_HUMAN (703-921): 8.11e-12: 71.9: 12.50