HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: PPWD1 (Q96BP3)
Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8) (Spliceosome-associated cyclophilin)
Gene: PPWD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	28524877
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 246 Hs			1 646
+	Hs
		729803 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		PPIL2_HUMAN (382-645): 2.5e-83: 273: 31.96
+	At
		840255 14331_ARATH (2-240): 2.72e-143: 403: 62.96		PNSL5_ARATH (459-644): 2.68e-80: 256: 38.86
+	At
		760719 14331_ARATH (2-240): 2.72e-143: 403: 62.96		CP18C_ARATH (487-644): 1.51e-77: 246: 42.60
+	Dm
		1019964 1433E_DROME (3-245): 4.65e-144: 405: 64.90		Q9W227_DROME (483-642): 5.88e-76: 243: 47.62
+	At
		760720 14333_ARATH (3-241): 4.46e-143: 402: 62.96		CP18C_ARATH (487-644): 1.51e-77: 246: 42.60
+	At
		840326 14331_ARATH (2-240): 2.72e-143: 403: 62.96		CP19B_ARATH (483-644): 1.09e-76: 244: 42.78
+	Hs
		971388 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		PPIA_HUMAN (486-644): 3.39e-76: 242: 43.56
+	Hs
		729732 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		PPIA_HUMAN (486-644): 3.39e-76: 242: 43.56
+	Hs
		986326 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		PPIA_HUMAN (486-644): 3.39e-76: 242: 43.56
+	At
		840394 14333_ARATH (3-241): 4.46e-143: 402: 62.96		CP19A_ARATH (483-644): 3.7e-74: 237: 41.04
+	Hs
		690974 1433T_HUMAN (3-244): 3.25e-127: 361: 81.82		PPIL2_HUMAN (382-645): 2.5e-83: 273: 31.96
+	Hs
		1049256 1433F_HUMAN (4-244): 2.72e-107: 311: 75.51		PPIL2_HUMAN (382-645): 2.5e-83: 273: 31.96
+	Hs
		964826 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		WDR5_HUMAN (175-406): 7.99e-50: 178: 13.77
+	Hs
		656050 1433S_HUMAN (3-239): 3.4e-100: 293: 68.62		PPIB_HUMAN (473-644): 2.66e-74: 239: 44.32
+	Hs
		845269 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		LIS1_HUMAN (255-486): 5.4e-20: 94.7: 10.12
+	Hs
		729664 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		LIS1_HUMAN (255-486): 5.4e-20: 94.7: 10.12
+	Hs
		845278 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		LIS1_HUMAN (255-486): 5.4e-20: 94.7: 10.12
+	Hs
		845265 1433G_HUMAN (3-246): 1.92e-109: 317: 75.40		LIS1_HUMAN (255-486): 5.4e-20: 94.7: 10.12
+	Hs
		845289 1433F_HUMAN (4-244): 2.72e-107: 311: 75.51		LIS1_HUMAN (255-486): 5.4e-20: 94.7: 10.12