HitPredict

Interactor 1: DAD2 (P36162)
DASH complex subunit DAD2 (DUO1 and DAM1-interacting protein 2) (Helper of ASK1 protein 1) (Outer kinetochore protein DAD2)
Gene: DAD2

Interactor 2: SPC19 (Q03954)
DASH complex subunit SPC19 (19 kDa spindle pole component protein) (Outer kinetochore protein SPC19)
Gene: SPC19

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.90	0.893

The method score is based on:

Property	Details
Experiments	11283351, 10655498, 11782438, 17634282, 16554755, 37968396
Identification Methods	two hybrid pooling approach, two hybrid, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	DASH_Dad2~DASH_Spc19
Common GO terms	GO:0005737 - cytoplasm GO:0008608 - attachment of spindle microtubules to kinetochore GO:0031116 - positive regulation of microtubule polymerization GO:0042729 - DASH complex GO:0051301 - cell division and 4 others more... GO:0051987 - positive regulation of attachment of spindle microtubules to kinetochore GO:0072686 - mitotic spindle GO:1990758 - mitotic sister chromatid biorientation GO:1990976 - protein transport along microtubule to mitotic spindle pole body
Homologous interactions	0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024