HitPredict

Interactor 1: ARL2 (P36404)
ADP-ribosylation factor-like protein 2
Gene: ARL2

Interactor 2: TBB8 (Q3ZCM7)
Tubulin beta-8 chain (Tubulin beta 8 class VIII)
Gene: TUBB8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005737 - cytoplasm GO:0015630 - microtubule cytoskeleton
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 184 Hs			1 444
+	Dm
		989450 ARL2_DROME (1-184): 2.09e-85: 250: 75.54		TBB1_DROME (1-429): 0: 718: 90.68
+	Dm
		989452 ARL2_DROME (1-184): 2.09e-85: 250: 75.54		Q8MST5_DROME (1-442): 0: 699: 83.33
+	Hs
		428053 ARL2_HUMAN (1-184): 2.36e-74: 222: 100.00		TBB5_HUMAN (1-429): 0: 720: 89.74
+	Hs
		734457 ARL2_HUMAN (1-184): 2.36e-74: 222: 100.00		TBB4B_HUMAN (1-427): 0: 719: 91.10
+	Hs
		734485 ARL2_HUMAN (1-184): 2.36e-74: 222: 100.00		TBB2B_HUMAN (1-430): 0: 719: 90.23
+	Hs
		381137 ARL2_HUMAN (1-184): 2.36e-74: 222: 100.00		TBB4A_HUMAN (1-427): 0: 715: 90.16
+	Hs
		734463 ARL2_HUMAN (1-184): 2.36e-74: 222: 100.00		TBB2A_HUMAN (1-430): 0: 715: 90.00
+	Dm
		897432 ARF1_DROME (1-178): 1.6e-73: 220: 46.37		TBB2_DROME (1-430): 0: 709: 89.54
+	Hs
		895072 RAB2A_HUMAN (11-183): 9.46e-65: 199: 21.35		TBB2A_HUMAN (1-430): 0: 715: 90.00