Interactor 1: VATE1 (P36543)
V-type proton ATPase subunit E 1 (V-ATPase subunit E 1) (V-ATPase 31 kDa subunit) (p31) (Vacuolar proton pump subunit E 1)
Gene: ATP6V1E1

Interactor 2: VATC2 (Q8NEY4)
V-type proton ATPase subunit C 2 (V-ATPase subunit C 2) (Vacuolar proton pump subunit C 2)
Gene: ATP6V1C2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains V-ATPase_C~vATP-synt_E
Common GO terms GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain
GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0016241 - regulation of macroautophagy
GO:0046961 - proton-transporting ATPase activity, rotational mechanism
and 1 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 226
Hs

1 427
+ Hs
+ Hs
+ Sc
+ Dm

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Last updated: 15 Jul 2024