HitPredict

Interactor 1: VATE1 (P36543)
V-type proton ATPase subunit E 1 (V-ATPase subunit E 1) (V-ATPase 31 kDa subunit) (p31) (Vacuolar proton pump subunit E 1)
Gene: ATP6V1E1

Interactor 2: VATH (Q9UI12)
V-type proton ATPase subunit H (V-ATPase subunit H) (Nef-binding protein 1) (NBP1) (Protein VMA13 homolog) (V-ATPase 50/57 kDa subunits) (Vacuolar proton pump subunit H) (Vacuolar proton pump subunit SFD)
Gene: ATP6V1H

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.853

The method score is based on:

Property Details
Experiments 12163484, 33961781, 35271311
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains V-ATPase_H_N~vATP-synt_E
Common GO terms GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain
GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0016241 - regulation of macroautophagy
GO:0030665 - clathrin-coated vesicle membrane
and 4 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 226
Hs

1 483
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024